M
Millissia Ben Maamar
Researcher at Washington State University
Publications - 32
Citations - 1026
Millissia Ben Maamar is an academic researcher from Washington State University. The author has contributed to research in topics: Epigenetics & DNA methylation. The author has an hindex of 10, co-authored 26 publications receiving 590 citations. Previous affiliations of Millissia Ben Maamar include University of Rennes & French Institute of Health and Medical Research.
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Journal ArticleDOI
Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.
Séverine Mazaud-Guittot,Christophe Nicolas Nicolaz,Christèle Desdoits-Lethimonier,Isabelle Coiffec,Millissia Ben Maamar,Patrick Balaguer,David Møbjerg Kristensen,David Møbjerg Kristensen,Cécile Chevrier,Vincent Lavoué,Patrice Poulain,Nathalie Dejucq-Rainsford,Bernard Jégou,Bernard Jégou +13 more
TL;DR: It is suggested that the fetal human testis displays slight critical age windows for sensitivity to direct exposure to aspirin, indomethacin, and paracetamol, and analgesics at concentrations relevant to human exposure cause endocrine disturbances in the fetal testis.
Journal ArticleDOI
Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease.
Michael K. Skinner,Millissia Ben Maamar,Ingrid Sadler-Riggleman,Daniel Beck,Eric E. Nilsson,Margaux McBirney,Rachel Klukovich,Yeming Xie,Chong Tang,Wei Yan +9 more
TL;DR: All three different epigenetic processes were concurrently altered as DDT induced the epigenetic transgenerational inheritance of sperm epimutations, demonstrating all three epigenetic Processes are involved in transGenerational inheritance.
Journal ArticleDOI
Alterations in sperm DNA methylation, non-coding RNA expression, and histone retention mediate vinclozolin-induced epigenetic transgenerational inheritance of disease.
Millissia Ben Maamar,Ingrid Sadler-Riggleman,Daniel Beck,Margaux McBirney,Eric E. Nilsson,Rachel Klukovich,Yeming Xie,Chong Tang,Wei Yan,Michael K. Skinner +9 more
TL;DR: Investigation of the vinclozolin-induced concurrent alterations of a number of different epigenetic factors, including DNA methylation, ncRNA, and histone retention in rat sperm shows that the three different types of epimutations are involved and integrated in the mediation of the epigenetic transgenerational inheritance phenomenon.
Journal ArticleDOI
Epigenetic Transgenerational Inheritance of Altered Sperm Histone Retention Sites
TL;DR: Observations demonstrate that in addition to alterations in sperm DNA methylation and ncRNA previously identified, the induction of differential histone retention sites (DHRs) also appear to be involved in environmentally induced epigenetic transgenerational inheritance.
Journal ArticleDOI
Ibuprofen results in alterations of human fetal testis development
Millissia Ben Maamar,Laurianne Lesné,Kristin Hennig,Christèle Desdoits-Lethimonier,Karen R. Kilcoyne,Isabelle Coiffec,Antoine Rolland,Cécile Chevrier,David Møbjerg Kristensen,David Møbjerg Kristensen,Vincent Lavoué,Jean-Philippe Antignac,Bruno Le Bizec,Nathalie Dejucq-Rainsford,Rod T. Mitchell,Séverine Mazaud-Guittot,Bernard Jégou,Bernard Jégou +17 more
TL;DR: It is concluded that, at concentrations relevant to human exposure and within a particular narrow ‘early window’ of sensitivity within first trimester, ibuprofen causes direct endocrine disturbances in the human fetal testis and alteration of the germ cell biology.