Ingunn Tho

TL;DR: Liposomes as nanosized phospholipid-based vesicles are expected to solubilize curcumin and enhance its activity, thus serving as an advanced topical formulation in the treatment of vaginal inflammation.

TL;DR: This study indicates that the camptothecin-loaded solid lipid nanoparticles (SLN) are a promising drug brain delivery system worth to explore further for brain tumour therapy.

TL;DR: It was concluded that dispersion of melt extrudates in aqueous medium give rise to nano/ micro-dispersions and the stability of the nano/micro-dispersion is sensitive to anions and may be subjected to association/aggregation/flocculation as time proceeds after preparation of dispersion.

TL;DR: Ex vivo penetration experiments performed on the pregnant sheep vaginal tissue showed that coated liposomes assured increased clotrimazole tissue retention and reduced its penetration as compared to the control, providing a good platform for further in vivo animal studies on mucoadhesive liposome destined to localized vaginal therapy.

TL;DR: The ability of this approach to quantify compression behavior, as a step towards a 'formulation development tool' for tablets, is shown.