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Irena Novakova
Researcher at Radboud University Nijmegen Medical Centre
Publications - 48
Citations - 1785
Irena Novakova is an academic researcher from Radboud University Nijmegen Medical Centre. The author has contributed to research in topics: Venous thrombosis & Thrombosis. The author has an hindex of 21, co-authored 48 publications receiving 1717 citations. Previous affiliations of Irena Novakova include Radboud University Nijmegen.
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The Nijmegen Modification of the Bethesda Assay for Factor VIII : C Inhibitors: Improved Specificity and Reliability
Bert Verbruggen,Irena Novakova,Hans J. C. T. Wessels,Jan B.M. Boezeman,Marijke van den Berg,Eveline P. Mauser-Bunschoten +5 more
TL;DR: Two modifications are proposed and tested to resolve the imperfections of the Bethesda assay and allow better discrimination between positive and negative samples and improve reliability.
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Reliability of five rapid D-dimer assays compared to ELISA in the exclusion of deep venous thrombosis.
M.C.H. Janssen,A.E. Heebels,M. de Metz,H.W. Verbruggen,H.C.H. Wollersheim,Stefan Janssen,M.M.J. Schuurmans,Irena Novakova +7 more
TL;DR: The results suggest that VIDAS and Tinaquant may be used instead of ELISA DD in the exclusion of DVT and might be used as a routine screening test and should be evaluated in large clinical management studies.
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Hyperhomocysteinemia and other thrombotic risk factors in women with placental vasculopathy.
E.F. van der Molen,Bert Verbruggen,Irena Novakova,Tom K.A.B. Eskes,L.A.H. Monnens,Henk J. Blom +5 more
TL;DR: This study aims to investigate coagulation inhibitors and abnormalities of the homocysteine metabolism, which are related to an increased thrombotic risk, as risk factors for placental vasculopathy.
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Meloxicam, 15 mg/day, spares platelet function in healthy volunteers.
TL;DR: To study the influence of meloxicam, a cyclooxygenase‐2 (COX‐2) preferential nonsteroidal anti‐inflammatory drug, on serum thromboxane and platelet function in healthy volunteers with use of the maximum recommended daily dosage of 15 mg/day.
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Homozygous Cystathionine β-Synthase Deficiency, Combined With Factor V Leiden or Thermolabile Methylenetetrahydrofolate Reductase in the Risk of Venous Thrombosis
Leo A. J. Kluijtmans,Godfried H.J. Boers,Bert Verbruggen,Frans J.M. Trijbels,Irena Novakova,Henk J. Blom +5 more
TL;DR: Data indicate that FVL is not an absolute prerequisite and probably not even a major determinant of venous thrombosis in homocystinuria, but thermolabile MTHFR may constitute a significant risk factor for thromboembolic complications in this inborn error of methionine metabolism.