J
Jan B.M. Boezeman
Researcher at Radboud University Nijmegen Medical Centre
Publications - 101
Citations - 4835
Jan B.M. Boezeman is an academic researcher from Radboud University Nijmegen Medical Centre. The author has contributed to research in topics: Psoriasis & Population. The author has an hindex of 34, co-authored 101 publications receiving 4606 citations. Previous affiliations of Jan B.M. Boezeman include Radboud University Nijmegen.
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Journal ArticleDOI
Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy
I. Jolanda M. de Vries,W. Joost Lesterhuis,Jelle O. Barentsz,Pauline Verdijk,J. Han van Krieken,Otto C. Boerman,Wim J.G. Oyen,Johannes J. Bonenkamp,Jan B.M. Boezeman,Gosse J. Adema,Jeff W.M. Bulte,Tom W. J. Scheenen,Cornelis J. A. Punt,Arend Heerschap,Carl G. Figdor +14 more
TL;DR: In vivo magnetic resonance tracking of magnetically labeled cells is feasible in humans for detecting very low numbers of dendritic cells in conjunction with detailed anatomical information and appears clinically safe and well suited to monitor cellular therapy in humans.
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The Nijmegen Modification of the Bethesda Assay for Factor VIII : C Inhibitors: Improved Specificity and Reliability
Bert Verbruggen,Irena Novakova,Hans J. C. T. Wessels,Jan B.M. Boezeman,Marijke van den Berg,Eveline P. Mauser-Bunschoten +5 more
TL;DR: Two modifications are proposed and tested to resolve the imperfections of the Bethesda assay and allow better discrimination between positive and negative samples and improve reliability.
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Psoriasis of the nails associated with disability in a large number of patients: Results of a recent interview with 1,728 patients
TL;DR: It is indicated that psoriasis of the nails is a more important individual and social-economic problem than previously assumed and that development of new treatments is needed.
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Haploinsufficiency of TNXB Is Associated with Hypermobility Type of Ehlers-Danlos Syndrome
Manon C. Zweers,James Bristow,Peter M. Steijlen,Willow B. Dean,Ben C.J. Hamel,M.E. Otero,M. Kucharekova,Jan B.M. Boezeman,Joost Schalkwijk +8 more
TL;DR: It is shown that deficiency of the extracellular-matrix protein tenascin-X (TNX), encoded by the TNXB gene, causes a new type of recessively inherited EDS, which is similar to benign joint hypermobility syndrome (BJHS).
Journal ArticleDOI
The tetraspanin CD37 orchestrates the alpha(4)beta(1) integrin-Akt signaling axis and supports long-lived plasma cell survival
Annemiek B. van Spriel,Sandra de Keijzer,Alie van der Schaaf,Kate H. Gartlan,Mariam Sofi,Amanda Light,Peter C. M. Linssen,Jan B.M. Boezeman,Malou Zuidscherwoude,Inge Reinieren-Beeren,Alessandra Cambi,Fabienne Mackay,David M. Tarlinton,Carl G. Figdor,Mark D. Wright +14 more
TL;DR: It is found that the four-transmembrane protein CD37 was essential for B cell survival and long-lived protective immunity and was required for the survival of IgG-secreting plasma cells in response to binding of vascular cell adhesion molecule 1 to the α4β1 integrin.