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Isaac Túnez
Researcher at University of Córdoba (Spain)
Publications - 145
Citations - 3707
Isaac Túnez is an academic researcher from University of Córdoba (Spain). The author has contributed to research in topics: Oxidative stress & Glutathione. The author has an hindex of 32, co-authored 129 publications receiving 3187 citations.
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Oxidative stress in diabetic rats induced by streptozotocin: Protective effects of melatonin
Pedro Montilla,José Fresno Vargas,Isaac Túnez,M. Carmen,Muñoz de Agueda,M. Elías Díaz Valdelvira,Emilio Cabrera +6 more
TL;DR: Melatonin reduces remarkably the degree of lipoperoxidation, hyperglycemia, and protein glycosylation, which gives hope to a promising perspective of this product, together with other biological antioxidants, in the treatment of diabetic complications where oxidative stress, either in a high or in a low degree, is present.
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3-Nitropropionic Acid as a Tool to Study the Mechanisms Involved in Huntington’s Disease: Past, Present and Future
TL;DR: This review will focus on the past and present research of 3-Nitropropionic acid, to finally bring a perspective on what will be next in this promising field of study.
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Peripheral oxidative stress in relapsing-remitting multiple sclerosis.
Inmaculada Tasset,Eduardo Agüera,Fernando Sánchez-López,Montserrat Feijóo,Ana I. Giraldo,Antonio H. Cruz,Félix Gascón,Isaac Túnez +7 more
TL;DR: Oxidative stress plays a major role in MS, and is observed prior to relapse, and was significantly higher in RR-MS patients than in healthy controls.
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Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study
Elena M. Yubero-Serrano,Javier Delgado-Lista,Patricia Peña-Orihuela,Pablo Perez-Martinez,Francisco Fuentes,Carmen Marin,Isaac Túnez,Francisco J. Tinahones,Francisco Pérez-Jiménez,Helen M. Roche,Jose Lopez-Miranda +10 more
TL;DR: In this article, the relationship between the number of MetS components and the degree of OxS in MetS patients was determined by measuring ischemic reactive hyperemia (IRH), plasma levels of soluble vascular cell adhesion molecule-1 (sVCAM-1), total nitrite, lipid peroxidation products (LPO), hydrogen peroxide (H2O2), superoxide dismutase (SOD), glutathione peroxidase (GPx) plasma activities.
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Hyperlipidemic nephropathy induced by adriamycin : Effect of melatonin administration
TL;DR: The results confirm the involvement of free radicals in the pathogenesis of nephrotoxicity induced by AD and show the high antioxidative power of MEL and its marked effect on the prevention and suppression of this nephropathy.