I
Isabel Cuesta
Researcher at Spanish National Research Council
Publications - 25
Citations - 1853
Isabel Cuesta is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Biology & Bifidobacterium. The author has an hindex of 12, co-authored 17 publications receiving 1528 citations. Previous affiliations of Isabel Cuesta include University of Pennsylvania & Fox Chase Cancer Center.
Papers
More filters
Journal ArticleDOI
Opening of Compacted Chromatin by Early Developmental Transcription Factors HNF3 (FoxA) and GATA-4
TL;DR: The ability of HNF3 to open chromatin is mediated by a high affinity DNA binding site and by the C-terminal domain of the protein, which binds histones H3 and H4.
Journal ArticleDOI
Monkeypox outbreak in Madrid (Spain): Clinical and virological aspects
Eva Orviz,Ana Isabel Negredo,Oskar Ayerdi,Ana Vázquez,Ana Muñoz Gómez,Sara Monzón,P. Clavo,Ángel Zaballos,Mar Vera,Patricia Mills Sánchez,Noemi Cabello,Pilar Jiménez,Jorge Pérez-García,Sarai Varona,Jorge del Romero,Isabel Cuesta,Alberto Delgado-Iribarren,M P Torres,Iñigo Sagastagoitia,Gustavo Palacios,Vicente Estrada,María Paz Sánchez-Seco +21 more
TL;DR: In this article , the authors performed an observational study of cases diagnosed in Madrid (Spain) (May/June 2022). Confirmation from vesicular lesions swabs, Orthopoxvirus real-time PCR, sequencing, phylogenetic analysis, and direct detection by Electron microscopy was performed.
Journal ArticleDOI
A fast, reliable, ultra high performance liquid chromatography method for the simultaneous determination of amino acids, biogenic amines and ammonium ions in cheese, using diethyl ethoxymethylenemalonate as a derivatising agent.
Begoña Redruello,Victor Ladero,Isabel Cuesta,Jorge R. Alvarez-Buylla,Maria Cruz Martin,María Dolores Lanzarote Fernández,Miguel A. Alvarez +6 more
TL;DR: Derivatisation treatment with diethyl ethoxymethylenemalonate followed by ultra-HPLC allowed the simultaneous quantification of 22 amino acids, 7 biogenic amines and ammonium ions in cheese samples in under 10 min, which is the fastest elution time ever reported for such a resolution.
Journal ArticleDOI
The forkhead factor FoxE1 binds to the thyroperoxidase promoter during thyroid cell differentiation and modifies compacted chromatin structure.
TL;DR: It is proposed that FoxE1 is a pioneer factor whose primary mechanistic role in mediating the hormonal regulation of the TPO gene is to enable other regulatory factors to access the chromatin.
Journal ArticleDOI
Integrase-Specific Enhancement and Suppression of Retroviral DNA Integration by Compacted Chromatin Structure In Vitro
Konstantin Taganov,Isabel Cuesta,René Daniel,Lisa Ann Cirillo,Richard A. Katz,Kenneth S. Zaret,Anna Marie Skalka +6 more
TL;DR: The results indicate that chromatin structure affects integration site selection of the HIV-1 and ASV integrases in opposite ways, resulting in an important bias against or in favor of integration into actively transcribed host DNA.