I
Isabel Méndez
Researcher at National Autonomous University of Mexico
Publications - 43
Citations - 816
Isabel Méndez is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Prolactin & Calcitriol. The author has an hindex of 14, co-authored 41 publications receiving 717 citations.
Papers
More filters
Journal ArticleDOI
Calcitriol affects hCG gene transcription in cultured human syncytiotrophoblasts.
David Barrera,Euclides Avila,Guillermo Hernández,Isabel Méndez,Leticia González,Ali Halhali,Fernando Larrea,Angélica Morales,Lorenza Díaz +8 more
TL;DR: Findings indicating there is a functional vitamin D endocrine system in the placenta, and specific effects of calcitriol acting through the VDR and the cAMP/PKA signaling pathway upon hCG expression and secretion, indicate that there is an autocrine regulator of hCG.
Journal ArticleDOI
Mechanistic Effects of Calcitriol in Cancer Biology.
TL;DR: This review addresses the different mechanisms of action involved in the antineoplastic effects of calcitriol in the context of cancer.
Journal ArticleDOI
Prolactin promotes cartilage survival and attenuates inflammation in inflammatory arthritis
Norma Adán,Jessica Guzmán-Morales,Maria G. Ledesma-Colunga,Sonia I. Perales-Canales,Andrés Quintanar-Stephano,Fernando López-Barrera,Isabel Méndez,Bibiana Moreno-Carranza,Jakob Triebel,Nadine Binart,Gonzalo Martínez de la Escalera,Stéphanie Thebault,Carmen Clapp +12 more
TL;DR: It is demonstrated that PRL inhibits the apoptosis of cultured chondrocytes in response to a mixture of proinflammatory cytokines by preventing the induction of p53 and decreasing the BAX/BCL-2 ratio through a NO-independent, JAK2/STAT3-dependent pathway.
Journal ArticleDOI
Regulation of Vitamin D hydroxylases gene expression by 1,25-dihydroxyvitamin D3 and cyclic AMP in cultured human syncytiotrophoblasts.
Euclides Avila,Lorenza Díaz,David Barrera,Ali Halhali,Isabel Méndez,Leticia González,Ulrich Zuegel,Andreas Steinmeyer,Fernando Larrea +8 more
TL;DR: The overall data suggest that calcitriol downregulates CYP27B1 expression via a cAMP-dependent signaling pathway, whereas upregulates 24-hydroxylase gene expression through a VDR-dependent mechanism.
Journal ArticleDOI
Prolactin promotes oxytocin and vasopressin release by activating neuronal nitric oxide synthase in the supraoptic and paraventricular nuclei
Claudia C. Vega,Bibiana Moreno-Carranza,Miriam Zamorano,Andrés Quintanar-Stephano,Isabel Méndez,Stéphanie Thebault,Gonzalo Martínez de la Escalera,Carmen Clapp +7 more
TL;DR: It is suggested that PRL enhances nNOS activity in the PVN and SON, thereby contributing to the regulation of OXT and AVP release, which likely contributes to theregulation of processes beyond those of female reproduction.