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Isabelle Loubinoux
Researcher at University of Toulouse
Publications - 73
Citations - 4827
Isabelle Loubinoux is an academic researcher from University of Toulouse. The author has contributed to research in topics: Stroke & Motor cortex. The author has an hindex of 31, co-authored 69 publications receiving 4359 citations. Previous affiliations of Isabelle Loubinoux include Centre national de la recherche scientifique & Paul Sabatier University.
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Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial
François Chollet,J. Tardy,Jean-François Albucher,Claire Thalamas,Emilie Bérard,Catherine Lamy,Yannick Béjot,Sandrine Deltour,Assia Jaillard,Philippe Niclot,Benoit Guillon,Thierry Moulin,Philippe Marque,Philippe Marque,Philippe Marque,Jérémie Pariente,Catherine Arnaud,Isabelle Loubinoux,Isabelle Loubinoux,Isabelle Loubinoux +19 more
TL;DR: In patients with ischaemic stroke and moderate to severe motor deficit, the early prescription of fluoxetine with physiotherapy enhanced motor recovery after 3 months.
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Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke.
Jérémie Pariente,Isabelle Loubinoux,Christophe Carel,Jean-François Albucher,Anne Leger,Claude Manelfe,Olivier Rascol,François Chollet +7 more
TL;DR: It was found that a single dose of fluoxetine was enough to modulate cerebral sensory‐motor activation in patients and this redistribution of activation toward the motor cortex output activation was associated with an enhancement of motor performance.
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A longitudinal fMRI study: in recovering and then in clinically stable sub-cortical stroke patients.
David Tombari,Isabelle Loubinoux,Jérémie Pariente,Angélique Gerdelat,Jean-François Albucher,J. Tardy,Emmanuelle Cassol,François Chollet +7 more
TL;DR: Despite clinical stability, changes in brain processing seemed to occur between E2 and E3 corresponding to a normalization of ipsilesional S1M1 activation, a decrease of bilateral cerebellar activation, and a progressive increase in SII-BA 40 activity suggesting evolving compensatory networks to sustain recovery.
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Post-stroke depression: mechanisms, translation and therapy.
Isabelle Loubinoux,Golo Kronenberg,Matthias Endres,Pascale Schumann-Bard,Thomas Freret,Robert K. Filipkowski,Leszek Kaczmarek,Aurel Popa-Wagner +7 more
TL;DR: Animal models of PSD are presented and potential underlying mechanisms including genomic signatures, neurotransmitter and neurotrophin signalling, hippocampal neurogenesis, cellular plasticity in the ischaemic lesion, secondary degenerative changes, activation of the hypothalamo‐pituitary‐adrenal (HPA) axis and neuroinflammation are summarized.
Journal ArticleDOI
Correlation between cerebral reorganization and motor recovery after subcortical infarcts.
Isabelle Loubinoux,Christophe Carel,Jérémie Pariente,Sophie Dechaumont,Jean-François Albucher,Philippe Marque,Claude Manelfe,François Chollet +7 more
TL;DR: The whole sensorimotor network activation correlated with motor status at E2, indicating a recovery of its function when activated, and demonstrated early functionality of the sensorsimotor system.