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Iván Chavarría-Siles
Researcher at VU University Amsterdam
Publications - 5
Citations - 180
Iván Chavarría-Siles is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Heterotrimeric G protein & Cognition. The author has an hindex of 5, co-authored 5 publications receiving 169 citations. Previous affiliations of Iván Chavarría-Siles include University of Texas Health Science Center at San Antonio & Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Cannabinoid receptor 1 gene (CNR1) and susceptibility to a quantitative phenotype for hebephrenic schizophrenia
Iván Chavarría-Siles,Javier Contreras-Rojas,Javier Contreras-Rojas,Elizabeth Hare,Consuelo Walss-Bass,Paulina Quezada,Albana M Dassori,Salvador Contreras,Rolando Medina,Mercedes Ramirez,Rodolfo Salazar,Henriette Raventós,Michael Escamilla +12 more
TL;DR: Schizophrenic subjects with prominent lifetime scores for disorganization and negative symptoms (dimension for hebephrenia) are associated with the CNR1 gene and present a type of symptomatology that resembles chronic cannabinoid‐induced psychosis, which points to the possibility of different genetic and pathophysiologic mechanisms underlying different types of schizophrenia.
Journal ArticleDOI
Methionine sulfoxide reductase: A novel schizophrenia candidate gene†
Consuelo Walss-Bass,Maria Clara Soto-Bernardini,Teresa L. Johnson-Pais,Robin J. Leach,Alfonso Ontiveros,Humberto Nicolini,Ricardo Mendoza,Alvaro Jerez,Albana M Dassori,Iván Chavarría-Siles,Michael Escamilla,Henriette Raventós +11 more
TL;DR: In this article, the authors identified a potential three-marker at risk haplotype within MSRA in the same CVCR sample, with a global P-value slightly above nominal significance (P = 0.0526).
Journal ArticleDOI
Myelination-related genes are associated with decreased white matter integrity in schizophrenia
Iván Chavarría-Siles,Tonya White,Christiaan de Leeuw,Christiaan de Leeuw,Andrea Goudriaan,Esther S. Lips,Stefan Ehrlich,Jessica A. Turner,Vince D. Calhoun,Randy L. Gollub,Vincent A. Magnotta,Beng-Choon Ho,August B. Smit,Mark H. G. Verheijen,Danielle Posthuma,Danielle Posthuma,Danielle Posthuma +16 more
TL;DR: The hypothesis that multiple genetic variants in myelination-related genes contribute to the observed correlation between schizophrenia and decreased WM integrity as measured by FA is supported.
Journal ArticleDOI
Genes Encoding Heterotrimeric G-proteins Are Associated with Gray Matter Volume Variations in the Medial Frontal Cortex
Iván Chavarría-Siles,Mark Rijpkema,Esther S. Lips,Alejandro Arias-Vásquez,Matthijs Verhage,Barbara Franke,Guillén Fernández,Danielle Posthuma +7 more
TL;DR: Voxel-based morphometry revealed a strong replicated association between 2 genes encoding heterotrimeric G-proteins with specific local increase in medial frontal cortex volume, an area known to be involved in cognitive control and negative affect, which suggests that heterot rimic G- Proteins might modulate medial frontal cortical gray matter volume.
Book ChapterDOI
Brain Imaging and Cognition
TL;DR: This chapter provides an overview of the most commonly used imaging techniques to study brain anatomy, connectivity, and functionality and reviews how neuroimaging techniques have been used to elucidate the development of the brain across lifespan and its relation to cognitive function.