T
Teresa L. Johnson-Pais
Researcher at University of Texas Health Science Center at San Antonio
Publications - 70
Citations - 2822
Teresa L. Johnson-Pais is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 24, co-authored 66 publications receiving 2517 citations. Previous affiliations of Teresa L. Johnson-Pais include University of Texas at Austin & Oregon Health & Science University.
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Journal ArticleDOI
Mechanism of calcium gating in small-conductance calcium-activated potassium channels
X. M. Xia,Bernd Fakler,Andre F. Rivard,Gary A. Wayman,Teresa L. Johnson-Pais,J. E. Keen,Takahiro M. Ishii,Birgit Hirschberg,Chris T. Bond,Svetlana Lutsenko,James Maylie,John P. Adelman +11 more
TL;DR: The mechanism of calcium gating is studied and it is found that small-conductance calcium-activated potassium channels are not gated by calcium binding directly to the channel α-subunits, instead, the functional SK channels are heteromeric complexes with calmodulin, which is constitutively associated with the α- subunits in a calcium-independent manner.
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L-2-Hydroxyglutarate: An Epigenetic Modifier and Putative Oncometabolite in Renal Cancer
Eun Hee Shim,Carolina B. Livi,Dinesh Rakheja,Jubilee Tan,Daniel Benson,Vishwas Parekh,Eun Young Kho,Arindam P. Ghosh,Richard Kirkman,Sadanan Velu,Shilpa Dutta,Balachandra Chenna,Shane L. Rea,Robert J. Mishur,Qiuhua Li,Teresa L. Johnson-Pais,Lining Guo,Sejong Bae,Shi Wei,Karen Block,Karen Block,Sunil Sudarshan +21 more
TL;DR: Elevations of the putative oncometabolite l-2HG in the most common subtype of kidney cancer are reported and a novel mechanism for the regulation of DNA 5hmC levels is described.
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A Single Nucleotide Polymorphism in MGEA5 Encoding O-GlcNAc–selective N-Acetyl-β-d Glucosaminidase Is Associated With Type 2 Diabetes in Mexican Americans
Donna M. Lehman,Dong Jing Fu,Angela B. Freeman,Kelly J. Hunt,Robin J. Leach,Teresa L. Johnson-Pais,Jeanette Hamlington,Thomas D. Dyer,Rector Arya,Hanna E. Abboud,Harald H H Göring,Ravindranath Duggirala,John Blangero,Robert J. Konrad,Michael P. Stern +14 more
TL;DR: Results suggest that this variant within the MGEA5 gene may increase diabetes risk in Mexican Americans, and may be responsible for the original linkage signal.
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Three Novel Mutations in SQSTM1 Identified in Familial Paget's Disease of Bone
Teresa L. Johnson-Pais,Julie H Wisdom,Korri S. Weldon,Jannine D. Cody,Marc F. Hansen,Frederick R. Singer,Robin J. Leach +6 more
TL;DR: The coding sequence of SQSTM1 was examined in five PDB pedigrees and three novel mutations clustered around the C‐terminal ubiquitin associated domain seem to be a leading cause of familial PDB.
Journal ArticleDOI
Metabolic Biosynthesis Pathways Identified from Fecal Microbiome Associated with Prostate Cancer.
Michael A. Liss,James R. White,Martin Goros,Jonathan Gelfond,Robin J. Leach,Teresa L. Johnson-Pais,Zhao Lai,Elizabeth Rourke,Joseph W. Basler,Donna P. Ankerst,Dimpy P. Shah +10 more
TL;DR: The study provides a basis to investigate the manipulation of aberrant microbiomes to reduce prostate cancer risk, and formed a novel microbiome-derived risk factor for prostate cancer based on 10 aberrant metabolic pathways.