Ivo Volf

TL;DR: The results on OxLDL-mediated platelet–monocyte aggregate formation, which promoted phenotypic changes in monocytes, monocyte extravasation and enhanced foam cell formation in vitro and in vivo, provide a novel mechanism for how platelets potentiate key steps of atherosclerotic plaque development and plaque destabilization.

TL;DR: Evidence that HDL retroendocytosis represents one of the pathways for cholesterol efflux is presented, as well as three physiologically relevant cell systems, including the liver cell line HepG2, the adrenal cell line Y1BS1, and phorbol myristate acetate-differentiated THP-1 cells as a model for macrophages.

TL;DR: It is proved that platelet TLR2 is important for formation of platelet–neutrophil aggregates and enhanced phagocytosis of periodontopathogens and requires functionalTLR2.

TL;DR: Although there are apparent discrepancies regarding the reported effects of acute, strenuous exercise on platelet activation, a deeper analysis of the available literature reveals that the applied exercise intensity and the subjects' cardiorespiratory fitness represent critical determinants for the observed effects.

TL;DR: Aqueous extracts from costi amari radix and the outer cover of myrobalani fructus, constituents of the complex herb preparation Padma 28, were found to inhibit inducible nitric oxide synthesis by decreasingiNOS protein and iNOS mRNA levels.