Iwona Lesiak-Markowicz

TL;DR: In this article, the authors demonstrate a mechanism mediating a strong IFN-β response in mouse conventional dendritic cells challenged by Candida spp., subsequently orchestrating IFNα/β receptor 1-dependent intracellular STAT1 activation and IFN regulatory factor (IRF) 7 expression.

TL;DR: A novel mechanism mediating a strong IFN-β response in mouse conventional dendritic cells challenged by Candida spp.

TL;DR: The results provide a first insight into the distribution of symbionts in TV isolates from Austrian patients and determine their effect on metronidazole susceptibility and cytotoxicity against HeLa cells.

TL;DR: In this paper , 654 leftovers of standard urine samples from healthy, asymptomatic Austrian soldiers were investigated for the prevalence of Trichomonas vaginalis, Chlamydia trachomatis , and genital mycoplasmas (mycoplasma hominis, Mycplasma genitalium, Ureaplasma urealyticum, U.S. prostate, Ureplasma parvum, and Candidatus Mycoplaa girerdii) by specific PCRs.

TL;DR: In this article , the authors evaluated and compared the most widely used cytotoxicity assays for their suitability to assess Acanthamoeba cytopathogenicity, and showed that cell-based assays using the aqueous soluble tetrazolium-formazan, and the NanoLuc® Luciferase prosubstrate products, in contrast to LDH, are excellent markers to monitor the interaction of Acanthamoneba with human cell lines and to determine and quantify effectively the cytotoxic effect induced by the amoebae.