J
J. A. H. Wass
Researcher at St Bartholomew's Hospital
Publications - 114
Citations - 5434
J. A. H. Wass is an academic researcher from St Bartholomew's Hospital. The author has contributed to research in topics: Acromegaly & Somatostatin. The author has an hindex of 40, co-authored 114 publications receiving 5327 citations.
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Journal ArticleDOI
Turner’s Syndrome in Adulthood
TL;DR: All adults with Turner's syndrome should be followed up by a multidisciplinary team to improve life expectancy and reduce morbidity.
Journal ArticleDOI
Primary medical therapy for acromegaly: an open, prospective, multicenter study of the effects of subcutaneous and intramuscular slow-release octreotide on growth hormone, insulin-like growth factor-I, and tumor size.
John S. Bevan,Stephen L. Atkin,A. B. Atkinson,P.-M. G. Bouloux,F. Hanna,P. E. Harris,R. A. James,M. McConnell,G. A. Roberts,Maurice F. Scanlon,Paul M. Stewart,E. Teasdale,H. E. Turner,J. A. H. Wass,Joanna M. Wardlaw +14 more
TL;DR: Primary medical therapy with Oct offers the prospect of normalization of GH/IGF-I levels together with substantial tumor shrinkage in a significant subset of acromegalic patients.
Journal ArticleDOI
Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome.
J. A. Verhelst,Peter J Trainer,Trevor A. Howlett,L. Perry,L. H. Rees,Ashley B. Grossman,J. A. H. Wass,G. M. Besser +7 more
TL;DR: The objective to analyse the clinical and biochemical effects of metyrapone in the treatment of Cushing's syndrome and to propose a new drug candidate for this indication.
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Outcome of transsphenoidal surgery for acromegaly using strict criteria for surgical cure
R. Sheaves,Paul J. Jenkins,P. Blackburn,A. H. Huneidi,F. Afshar,S. Medbak,Ashley B. Grossman,G. M. Besser,J. A. H. Wass +8 more
TL;DR: The results of transsphenoidal pituitary surgery for acromegaly were analyzed to assess the longer‐term outcome for patients not offered further treatment when post‐operative levels of GH < 5 mU/l were achieved.
Journal ArticleDOI
Circadian variation of GH-independent IGF-binding protein in diabetes mellitus and its relationship to insulin. A new role for insulin?
Jeffrey M P Holly,R A Biddlecombe,David B. Dunger,J A Edge,Stephanie A. Amiel,R. Howell,Tim Chard,L. H. Rees,J. A. H. Wass +8 more
TL;DR: Evidence is accumulating that a non‐GH dependent insulin‐like growth factor‐like Growth factor‐binding protein (IGF‐BP) is not only a carrier protein but also has an active role in the growth process.