J
J. Andrew Bradley
Researcher at University of Cambridge
Publications - 79
Citations - 5842
J. Andrew Bradley is an academic researcher from University of Cambridge. The author has contributed to research in topics: Transplantation & Kidney transplantation. The author has an hindex of 34, co-authored 79 publications receiving 5080 citations. Previous affiliations of J. Andrew Bradley include National Institute for Health Research & Cambridge University Hospitals NHS Foundation Trust.
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Journal ArticleDOI
Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching
Craig J. Taylor,Eleanor M. Bolton,Susan Pocock,Linda D. Sharples,Roger A. Pedersen,J. Andrew Bradley +5 more
TL;DR: How many hES cell lines would be needed to make matching possible in most cases for HLA matching is investigated, and the findings have practical, political, and ethical implications for the establishment of hES-cell banks.
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Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation.
TL;DR: Avoiding excessive immunosuppressive therapy may help minimise the risk of PTLD and EBV vaccination may in the future prove an effective prophylaxis against EBV-driven PTLD.
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Immunosuppressive agents in solid organ transplantation: Mechanisms of action and therapeutic efficacy.
TL;DR: An overview of the different immunosuppressive agents currently used in solid organ transplantation is provided and many of the key clinical trials that underpin current clinical usage of these agents are described and side-effects are highlighted.
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Generating an iPSC bank for HLA-matched tissue transplantation based on known donor and recipient HLA types.
TL;DR: This model provides a practical approach for using existing HLA-typed samples to generate an iPSC stem cell bank that circumvents prospective typing of a large number of individuals.
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Analysis of factors that affect outcome after transplantation of kidneys donated after cardiac death in the UK: a cohort study.
Dominic M. Summers,Dominic M. Summers,Dominic M. Summers,Rachel J. Johnson,Joanne Allen,Susan V. Fuggle,Susan V. Fuggle,David Collett,Christopher J.E. Watson,Christopher J.E. Watson,J. Andrew Bradley,J. Andrew Bradley +11 more
TL;DR: Allocation policy for kidneys from cardiac-death donors should reduce cold ischaemic time, avoid large age mismatches between donors and recipients, and restrict use of kidneys poorly matched for HLA in young recipients.