J
J.C. Holstege
Researcher at Erasmus University Rotterdam
Publications - 21
Citations - 1705
J.C. Holstege is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Anterograde tracing & GABAergic. The author has an hindex of 16, co-authored 21 publications receiving 1643 citations.
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Ultrastructural study of the GABAergic, cerebellar, and mesodiencephalic innervation of the cat medial accessory olive: anterograde tracing combined with immunocytochemistry.
TL;DR: The rostral medial accessory olive of the cat was studied by using an ultrastructural technique combining wheat germ agglutinin–coupled horseradish peroxidase (WGA‐HRP) anterograde tracing and postembedding GABA immunocytochemistry.
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The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome
Rob Willemsen,Marianne Hoogeveen-Westerveld,Surya A. Reis,J.C. Holstege,Lies Anne Severijnen,Ingeborg M. Nieuwenhuizen,Mariëtte Schrier,Leontine van Unen,Flora Tassone,André T. Hoogeveen,Paul J. Hagerman,Edwin Mientjes,Ben A. Oostra +12 more
TL;DR: The observations in expanded-repeat mice support a direct role of the Fmr1 gene, by either CGG expansion per se or by mRNA level, in the formation of the inclusions and suggest a correlation between the presence of intranuclear inclusions in distinct regions of the brain and the clinical features in symptomatic premutation carriers.
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A new combination of WGA-HRP anterograde tracing and GABA immunocytochemistry applied to afferents of the cat inferior olive at the ultrastructural level.
TL;DR: The results suggest that most, if not all, of the WGA-HRP-labelled cerebellar terminals in the rostral medial accessory olive (MAO) and the roostral principal olive (PO) are GABAergic.
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Distribution of dopamine immunoreactivity in the rat, cat and monkey spinal cord.
TL;DR: It is concluded that DA is widely distributed within the spinal cord, with few differences between species, emphasizing that DA plays an important role as one of the monoamines that influences sensory input as well as autonomic and motor output at the spinal level.
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Mesodiencephalic and cerebellar terminals terminate upon the same dendritic spines in the glomeruli of the cat and rat inferior olive: An ultrastructural study using a combination of [3H]-leucine and wheat germ agglutinin coupled horseradish peroxidase anterograde tracing
TL;DR: The mesodiencephalic and cerebellar afferents in the rostral medial accessory and principal olive of the cat and rat were studied and it was found that the terminals from both afferent systems contacted the same dendritic spines.