J
J. Cristian Salgado
Researcher at University of Chile
Publications - 20
Citations - 620
J. Cristian Salgado is an academic researcher from University of Chile. The author has contributed to research in topics: Intestinal absorption & Protein purification. The author has an hindex of 14, co-authored 20 publications receiving 525 citations.
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Sustainability indicators for the assessment of eco-industrial parks: classification and criteria for selection
TL;DR: In this paper, the authors proposed four criteria constructed to be functional, clear, and adaptable to the application context: understanding, pragmatism, relevance, and partial representation of sustainability.
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Current insights on protein behaviour in hydrophobic interaction chromatography.
TL;DR: It could be possible to carry out computational experiments by varying the different operating conditions for the purification of a target protein; and then selecting the best conditions in silico and designing a rational protein purification process involving an HIC step.
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Methods of calculating protein hydrophobicity and their application in developing correlations to predict hydrophobic interaction chromatography retention
TL;DR: Different methodologies to estimate the hydrophobicity of a protein are reviewed, which have been related to the chromatographic behavior of proteins in HIC.
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Predicting the behaviour of proteins in hydrophobic interaction chromatography. 1: Using the hydrophobic imbalance (HI) to describe their surface amino acid distribution.
TL;DR: A new parameter, called hydrophobic imbalance (HI), obtained from the three-dimensional structure of proteins is introduced, which quantifies the displacement of the superficial geometric centre of the protein when the effect of the hydrophobicity of each amino acid is considered.
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Revealing Monoamine Oxidase B Catalytic Mechanisms by Means of the Quantum Chemical Cluster Approach.
Gerald Zapata-Torres,Angélica Fierro,Germán Barriga-González,J. Cristian Salgado,Cristian Celis-Barros +4 more
TL;DR: It is proposed that good substratessuch as BA and PEA might follow the hydride transfer pathway while poor substrates such as NBA prefer the polar nucleophilic mechanism, which might suggest that MAO B can act by both mechanisms.