J
J. David Spence
Researcher at Robarts Research Institute
Publications - 431
Citations - 20158
J. David Spence is an academic researcher from Robarts Research Institute. The author has contributed to research in topics: Stroke & Blood pressure. The author has an hindex of 67, co-authored 399 publications receiving 17671 citations. Previous affiliations of J. David Spence include University of Western Ontario & New York University.
Papers
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Journal ArticleDOI
Identifying Which Patients With Asymptomatic Carotid Stenosis Could Benefit From Intervention
TL;DR: The predictive value of microemboli detection on TCD for the identification of ACS patients at high risk for stroke has been validated by 2 independent studies and is further supported by a meta-analysis.
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Importance of sex and gender in atherosclerosis and cardiovascular disease.
J. David Spence,Louise Pilote +1 more
TL;DR: In this special issue of the journal, there are papers on bone health and coronary artery calcification, age and sex differences in the effect of parental stroke on the progression of carotid intimamedia thickness, macrophage subsets in the adipose tissue by sex and by reproductive age of women.
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Lipoprotein(a) Is Associated Differentially With Carotid Stenosis, Occlusion, and Total Plaque Area
Jonathan Klein,Robert A. Hegele,Daniel G. Hackam,Marlys L. Koschinsky,Murray W. Huff,J. David Spence +5 more
TL;DR: Lp(a) was a significant independent predictor of carotid stenosis and occlusion, but not ofCarotid plaque area, supporting the hypothesis that the effect of Lp (a) on atherogenesis and cardiovascular risk is largely related to thrombosis and impaired fibrinolysis.
Journal Article
1999 Canadian recommendations for the management of hypertension
Ross D. Feldman,Norman R.C. Campbell,Pierre Larochelle,Peter Bolli,Ellen Burgess,S. George Carruthers,John S. Floras,R. Brian Haynes,George Honos,Frans H. H. Leenen,Larry A. Leiter,Alexander G. Logan,Martin G. Myers,J. David Spence,Kelly B. Zarnke +14 more
TL;DR: The 1999 Canadian Recommendations for the Management of Hypertension endorse the greater use of non-office-based measures of blood pressure control and greater emphasis on the assessment of other atherosclerotic risk factors, both when considering prognosis in hypertension and in the choice of therapy.
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Drug interactions with grapefruit: Whose responsibility is it to warn the public?
TL;DR: It is necessary to select patients suitable for vaginal or laparoscopic mesh placement for intranasal administration based on prior history and once they provide informed consent for surgery.