J
J. David Spence
Researcher at Robarts Research Institute
Publications - 431
Citations - 20158
J. David Spence is an academic researcher from Robarts Research Institute. The author has contributed to research in topics: Stroke & Blood pressure. The author has an hindex of 67, co-authored 399 publications receiving 17671 citations. Previous affiliations of J. David Spence include University of Western Ontario & New York University.
Papers
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Angiotensin inhibition in renovascular disease: a population-based cohort study.
Daniel G. Hackam,M. Duong-Hua,Muhammad Mamdani,Muhammad Mamdani,Ping Li,Sheldon W. Tobe,J. David Spence,Amit X. Garg,Amit X. Garg +8 more
TL;DR: It is suggested that angiotensin inhibitors may improve prognosis in this setting at the expense of acute renal toxicity if the latter are selected in the management of RVD, renal function parameters should be assiduously followed.
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Nitrous oxide-induced increased homocysteine concentrations are associated with increased postoperative myocardial ischemia in patients undergoing carotid endarterectomy.
TL;DR: It was reconfirmed that intraoperative nitrous oxide is associated with postoperative increases in plasma homocysteine concentration and was associated with an increase in postoperative myocardial ischemia.
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The current epidemic of primary aldosteronism: causes and consequences.
J. David Spence,Norman M Kaplan +1 more
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Blood pressure gradients in cerebral arteries: a clue to pathogenesis of cerebral small vessel disease.
TL;DR: The marked pressure gradient across cerebral arteries should be taken into account when evaluating the pathogenesis of small WMIs on MRI, and have important implications for understanding small vessel disease.
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Validation of 3d ultrasound vessel wall volume: an imaging phenotype of carotid atherosclerosis
TL;DR: A new three-dimensional ultrasound measurement or phenotype of carotid atherosclerosis, vessel wall volume (VWV), which is a three- dimensional measurement of vessel wall thickness and plaque within thecarotid arteries measured in 3DUS images is developed and validated.