J
J. P. Reyftmann
Researcher at Centre national de la recherche scientifique
Publications - 10
Citations - 536
J. P. Reyftmann is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Hematoporphyrin & Quantum yield. The author has an hindex of 8, co-authored 10 publications receiving 535 citations.
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Journal ArticleDOI
Interaction of human serum low density lipoproteins with porphyrins: a spectroscopic and photochemical study
J. P. Reyftmann,Patrice Morlière,S. Goldstein,René Santus,Louis Dubertret,Dominique Lagrange +5 more
TL;DR: It can be concluded that hydrophobic porphyrins bind to blood proteins in patients suffering from protoporphyria.
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EXCITED STATE PROPERTIES OF ∝aL‐TERTHIENYL and RELATED MOLECULES
TL;DR: The hydrophobic thiophenes investigated are, therefore, Type II photodynamic agents almost exclusively.
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In vitro interaction of the photoactive anticancer porphyrin derivative photofrin II with low density lipoprotein, and its delivery to cultured human fibroblasts.
C. Candide,P. Morliere,J.C. Mazière,S. Goldstein,René Santus,Louis Dubertret,J. P. Reyftmann,Jacques Polonovski +7 more
TL;DR: A special role of the LDL‐receptor pathway in P2 delivery to cells is suggested and could be of interest in cancer phototherapy by porphyrins.
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Permeation of lysosomal membranes in the course of photosensitization with methylene blue and hematoporphyrin: Study by cellular microspectrofluorometry.
René Santus,Cahide Kohen,Elli Kohen,J. P. Reyftmann,Patrice Morlière,Louis Dubertret,P. M. Tocci +6 more
TL;DR: The high sensitivity of the fluorescence detection makes it possible to use 4‐methylumbelliferyl substrates for the enzymes contained in a single cell, leading to enzyme release accompanying strong morphological changes.
Journal ArticleDOI
Photosensitization by porphyrins delivered to L cell fibroblasts by human serum low density lipoproteins. A microspectrofluorometric study.
Patrice Morlière,Elli Kohen,J. P. Reyftmann,René Santus,Cahide Kohen,J.C. Mazière,S. Goldstein,Walter F. Mangel,Louis Dubertret +8 more
TL;DR: Topographic analysis by microspectrofluorometry on single living cells shows that after digestion of LDL, protoporphyrin is localized in cytoplasmic areas and fluorescent products have been previously identified as lipofuscin‐like pigments formed by reaction of lipid photoperoxides with amino groups.