J. S. Luther

TL;DR: The placenta is the organ that transports nutrients, respiratory gases, and wastes between the maternal and fetal systems and placental blood flow and vascular development are essential components of normal placental function and are critical to fetal growth and development.

TL;DR: The challenges will be to find biomarkers of abnormal placental angiogenesis and to develop therapeutic strategies to "rescue" placental vascular development and thus fetal growth in compromised pregnancies and animal models will be essential in meeting these challenges.

TL;DR: Various large animal models of developmental programming are discussed and how they have and will continue to contribute to the understanding of the mechanisms underlying altered placental function and developmental programming, and how largeAnimal models also will be critical to the identification and application of therapeutic strategies that will alleviate the negative consequences of developmental Programming to improve offspring performance in livestock production and human medicine.

TL;DR: Maternal intake at both ends of the nutritional spectrum is a powerful determinant of fetal growth in pregnant adolescents, particularly in adolescent girls who become pregnant with inadequate or marginal nutritional status during pregnancy.

TL;DR: Improper nutrition from mid to late pregnancy in ewe lambs altered colostrum quality and quantity and reduced offspring birth weight, which may have negative implications for lamb health and survival during the early postnatal period.