https://www.gastrojournal.org/article/S0016-5085(05)00630-X/pdf

Sampling variability of liver biopsy in nonalcoholic fatty liver disease.

https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(07)60439-5.pdf

Wilson's Disease

▪ Abstract Metallothioneins (MT) are low-molecular-weight, cysteine-rich, metal-binding proteins. MT genes are readily induced by various physiologic and toxicologic stimuli. Because the cysteines in MT are absolutely conserved across species, it was suspected that the cysteines are necessary for function and MT is essential for life. In attempts to determine the function(s) of MT, studies have been performed using four different experimental paradigms: (a) animals injected with chemicals known to induce MT; (b) cells adapted to survive and grow in high concentrations of MT-inducing toxicants; (c) cells transfected with the MT gene; and (d) MT-transgenic and MT-null mice. Most often, results from studies using the first three approaches have indicated multiple functions of MT in cell biology: MT (a) is a “storehouse” for zinc, (b) is a free-radical scavenger, and (c) protects against cadmium (Cd) toxicity. However, studies using MT-transgenic and null mice have not strongly supported the first two propose...

Metallothionein: an intracellular protein to protect against cadmium toxicity.

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.22261

Diagnosis and treatment of Wilson disease: an update.

Primary sclerosing cholangitis

Management of Wilson's disease with zinc sulphate. Experience in a series of 27 patients.

Budesonide or prednisone in combination with ursodeoxycholic acid in primary sclerosing cholangitis: a randomized double-blind pilot study

Duplex Doppler measurements of portal venous flow in normal subjects: Inter- and intra-observer variability

Budesonide or prednisone in combination with ursodeoxycholic acid in primary sclerosing cholangitis: a randomized double-blind pilot study. Belgian-Dutch PSC Study Group.

Relation between laboratory test results and histological hepatitis activity in individuals positive for hepatitis B surface antigen and antibodies to hepatitis B e antigen

J. van Hattum

Papers

Management of Wilson's disease with zinc sulphate. Experience in a series of 27 patients.

Budesonide or prednisone in combination with ursodeoxycholic acid in primary sclerosing cholangitis: a randomized double-blind pilot study

Duplex Doppler measurements of portal venous flow in normal subjects: Inter- and intra-observer variability

Budesonide or prednisone in combination with ursodeoxycholic acid in primary sclerosing cholangitis: a randomized double-blind pilot study. Belgian-Dutch PSC Study Group.

Relation between laboratory test results and histological hepatitis activity in individuals positive for hepatitis B surface antigen and antibodies to hepatitis B e antigen