J
J. W. J. Bijlsma
Researcher at University Medical Center Utrecht
Publications - 178
Citations - 8803
J. W. J. Bijlsma is an academic researcher from University Medical Center Utrecht. The author has contributed to research in topics: Rheumatoid arthritis & Cartilage. The author has an hindex of 52, co-authored 178 publications receiving 8414 citations.
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Journal ArticleDOI
Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed
L. B. A. Van De Putte,C Atkins,Michel Malaise,J Sany,Anthony S. Russell,P.L.C.M. van Riel,L. Settas,J. W. J. Bijlsma,S Todesco,Maxime Dougados,Peter Nash,Paul Emery,N Walter,M Kaul,S Fischkoff,H Kupper +15 more
TL;DR: Among patients with RA for whom previous DMARD treatment had failed, adalimumab monotherapy achieved significant, rapid, and sustained improvements in disease activity and improved physical function and was safe and well tolerated.
Journal ArticleDOI
Intensive treatment with methotrexate in early rheumatoid arthritis: aiming for remission. Computer Assisted Management in Early Rheumatoid Arthritis (CAMERA, an open-label strategy trial)
Suzanne M M Verstappen,J. W. G. Jacobs,M. J. Van Der Veen,A H M Heurkens,Y Schenk,E J ter Borg,A A M Blaauw,J. W. J. Bijlsma +7 more
TL;DR: The results of this study show that it is possible to substantially enhance the clinical efficacy early in the course of the disease by intensifying treatment with methotrexate, aiming for remission, tailored to the individual patient.
Journal ArticleDOI
The Effectiveness of Early Treatment with “Second-Line” Antirheumatic Drugs: A Randomized, Controlled Trial
A. van der Heide,J. W. G. Jacobs,J. W. J. Bijlsma,A H M Heurkens,C van Booma-Frankfort,M. J. Van Der Veen,H. C. M. Haanen,D. M. Hofman,G A van Albada-Kuipers,E J ter Borg,H L M Brus,H. J. Dinant,Aike A. Kruize,Y Schenk +13 more
TL;DR: The first-year results of a randomized clinical trial in which the delayed and the immediate introduction of SAARDs were compared are described and the consequences of ignoring the treatment pyramid for patients with recent-onset rheumatoid arthritis are investigated.
Journal ArticleDOI
Standardised nomenclature for glucocorticoid dosages and glucocorticoid treatment regimens: current questions and tentative answers in rheumatology
Frank Buttgereit,J. A. P. Da Silva,Maarten Boers,G.-R. Burmester,Maurizio Cutolo,J. W. G. Jacobs,John R. Kirwan,L. Kohler,P.L.C.M. van Riel,T. Vischer,J. W. J. Bijlsma +10 more
TL;DR: Recommendations on glucocorticoid treatment are presented that reflect current and best knowledge available and take into account current clinical practice.
Journal ArticleDOI
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis
R. N. J. de Nijs,J. W. G. Jacobs,Willem F. Lems,Roland Laan,A. Algra,A. M. Huisman,Erik Buskens,C.E.D. de Laet,Ans C. M. Oostveen,Piet Geusens,George A W Bruyn,B A C Dijkmans,J. W. J. Bijlsma +12 more
TL;DR: A randomized, double-placebo, double blind clinical trial of 18 months' duration among patients with a rheumatic disease who were starting glucocorticoids at a daily dose that was equivalent to at least 7.5 mg of prednisone, finding the bone mineral density of the lumbar spine increased in the alendronate group.