L
L. Settas
Researcher at Aristotle University of Thessaloniki
Publications - 9
Citations - 2755
L. Settas is an academic researcher from Aristotle University of Thessaloniki. The author has contributed to research in topics: Rheumatoid arthritis & Rheumatology. The author has an hindex of 6, co-authored 7 publications receiving 2676 citations.
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Journal ArticleDOI
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial
Lars Klareskog,Désirée van der Heijde,Julien P de Jager,A. K. S. Gough,Joachim R. Kalden,Michel Malaise,Emilio Martin Mola,Karel Pavelka,Jacques Sany,L. Settas,Joseph Wajdula,Ronald Pedersen,Saeed Fatenejad,Marie Sanda +13 more
TL;DR: The combination of etanercept and methotrexate was significantly better in reduction of disease activity, improvement of functional disability, and retardation of radiographic progression compared with methotRexate or etanorcept alone.
Journal ArticleDOI
Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed
L. B. A. Van De Putte,C Atkins,Michel Malaise,J Sany,Anthony S. Russell,P.L.C.M. van Riel,L. Settas,J. W. J. Bijlsma,S Todesco,Maxime Dougados,Peter Nash,Paul Emery,N Walter,M Kaul,S Fischkoff,H Kupper +15 more
TL;DR: Among patients with RA for whom previous DMARD treatment had failed, adalimumab monotherapy achieved significant, rapid, and sustained improvements in disease activity and improved physical function and was safe and well tolerated.
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Etanercept 50 mg once weekly is as effective as 25 mg twice weekly in patients with ankylosing spondylitis
D. van der Heijde,J.C. da Silva,Maxime Dougados,Pál Géher,I E van der Horst-Bruinsma,X. Juanola,I. Olivieri,F. Raeman,L. Settas,Joachim Sieper,Jacek Szechiński,David Walker,M. P. Boussuge,Joseph Wajdula,Laurence Paolozzi,S. Fatenejad +15 more
TL;DR: Patients with ankylosing spondylitis can expect a comparable significant improvement in clinical outcomes with similar safety when treated with etanercept 50 mg once weekly or with 25 mg twice weekly.
Journal ArticleDOI
Presentation and analysis of data on radiographic outcome in clinical trials: Experience from the TEMPO study
Désirée van der Heijde,Robert Landewé,Lars Klareskog,Vicente Rodriguez-Valverde,L. Settas,Ronald Pedersen,Saeed Fatenejad +6 more
TL;DR: A panel of alternative analysis methods and alternative ways of handling missing information are suggested to verify that the radiographic results reported in an randomized controlled trial are not influenced by technical factors, such as interpolation, handling of missing data, and choice of statistical tests.
Journal ArticleDOI
Guidelines for initiation of anti-tumour necrosis factor therapy in rheumatoid arthritis: similarities and differences across Europe
Paul Emery,R. van Vollenhoven,Mikkel Østergaard,Ernest Choy,B. Combe,Winfried Graninger,K. Krueger,Marco Matucci-Cerinic,F. Navarro,P.L.C.M. van Riel,L. Settas,Serge Steinfeld +11 more
TL;DR: A cross-sectional comparison of patients with RA in 15 different countries revealed great variation in the drug management, including the delay in starting a disease-modifying antirheumatic drug (DMARD) ranging from 12 months, use of methotrexate, and disease activity scores varied.