J
John R. Kirwan
Researcher at University of Bristol
Publications - 356
Citations - 19004
John R. Kirwan is an academic researcher from University of Bristol. The author has contributed to research in topics: Rheumatoid arthritis & Arthritis. The author has an hindex of 65, co-authored 355 publications receiving 17763 citations. Previous affiliations of John R. Kirwan include Bristol Royal Infirmary & University Hospitals Bristol NHS Foundation Trust.
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Journal ArticleDOI
American College of Rheumatology/European League Against Rheumatism Provisional Definition of Remission in Rheumatoid Arthritis for Clinical Trials
David T. Felson,David T. Felson,Josef S Smolen,George A. Wells,Bi Zhang,Lilian H D van Tuyl,Julia Funovits,Daniel Aletaha,Cornelia F Allaart,Joan M. Bathon,Joan M. Bathon,Stefano Bombardieri,Peter Brooks,Andrew K Brown,Marco Matucci-Cerinic,Hyon K. Choi,Bernard Combe,Maarten de Wit,Maxime Dougados,Paul Emery,Daniel E. Furst,Juan J. Gomez-Reino,Gillian A. Hawker,Edward C. Keystone,Dinesh Khanna,John R. Kirwan,Tore K Kvien,Robert Landewé,Joachim Listing,Kaleb Michaud,Emilio Martín-Mola,Pamela Montie,Theodore Pincus,Pamela Richards,Jeffrey Siegel,Jeffrey Siegel,Lee S. Simon,Tuulikki Sokka,Vibeke Strand,Peter Tugwell,Alan Tyndall,Désirée van der Heijde,S. M. M. Verstappen,Barbara White,Frederick Wolfe,Angela Zink,Maarten Boers +46 more
TL;DR: It is proposed that a patient's RA can be defined as being in remission based on one of two definitions: (1) when scores on the tender joint count, swollen joint counts, CRP level, and patient global assessment are all ≤1, or (2) when the score on the Simplified Disease Activity Index is ≤3.
Journal Article
Recommendations for a core set of outcome measures for future Phase III clinical trials in knee, hip, and hand osteoarthritis. Consensus development at OMERACT III
Nicholas Bellamy,John R. Kirwan,Maarten Boers,Peter Brooks,Vibeke Strand,Peter Tugwell,Roy D. Altman,Kenneth D. Brandt,Maxime Dougados,Michel Lequesne +9 more
TL;DR: A consensus was reached by at least 90% of participants that the following 4 domains should be evaluated in future phase III trials of knee, hip, and hand OA: pain, physical function, patient global assessment, and, for studies of one year or longer, joint imaging.
Journal ArticleDOI
Developing Core Outcome Measurement Sets for Clinical Trials: OMERACT Filter 2.0
Maarten Boers,John R. Kirwan,George A. Wells,Dorcas E. Beaton,Laure Gossec,Maria Antonietta D'Agostino,Philip G. Conaghan,Clifton O. Bingham,Peter Brooks,Robert Landewé,Lyn March,Lyn March,Lee S. Simon,Jasvinder A. Singh,Jasvinder A. Singh,Vibeke Strand,Peter Tugwell +16 more
TL;DR: The OMERACT Filter 2.0 explicitly describes a comprehensive conceptual framework and a recommended process to develop core outcome measurement sets for rheumatology likely to be useful as a template in other areas of health care.
Journal ArticleDOI
Determinants of disability in osteoarthritis of the knee.
TL;DR: Quadriceps strength, knee pain, and age are more important determinants of functional impairment in elderly subjects than the severity of knee osteoarthritis as assessed radiographically.
Journal ArticleDOI
Stanford health assessment questionnaire modified to assess disability in british patients with rheumatoid arthritis
John R. Kirwan,Jane S. Reeback +1 more
TL;DR: The Stanford Health Assessment Questionnaire was modified for use amongst British patients by the substitution of colloquial expressions to be more sensitive to patients' functional changes than the Steinbrocker grading.