J. W. J. Bijlsma

TL;DR: In this paper, a multidisciplinary guideline development group comprised 16 rheumatologists, one physiatrist, one orthopaedic surgeon, two allied health professionals, and one evidence-based medicine expert, representing 15 different European countries, contributed up to 10 propositions describing key clinical points for management of hand OA.

TL;DR: These are the first clinical guidelines on knee OA to combine an evidence based approach and a consensus approach across a wide range of treatment modalities and it is apparent that certain clinical propositions are supported by substantial research based evidence, while others are not.

TL;DR: 10 key recommendations for diagnosis of knee OA were developed using both research evidence and expert consensus and although there is no agreed reference standard, thorough clinical assessment alone can provide a confident rule-in diagnosis.

TL;DR: The use of hydroxychloroquine at a dose of 400 mg daily taken over a 12 month period does not have a worthwhile clinical benefit in patients with primary Sjögren's syndrome despite an improvement of hyperglobulinaemia and slight changes in the ESR and IgM.

TL;DR: In patients with haemophilic arthropathy, local synovial iron deposits are associated with increased catabolic activity, and the supernatant fluids from the cultures showed greaterCatabolic activity from haemosideritic tissue, as determined by the inhibition of the synthesis of articular cartilage matrix.