B
Barry Bresnihan
Researcher at University College Dublin
Publications - 227
Citations - 17469
Barry Bresnihan is an academic researcher from University College Dublin. The author has contributed to research in topics: Rheumatoid arthritis & Arthritis. The author has an hindex of 73, co-authored 227 publications receiving 16561 citations. Previous affiliations of Barry Bresnihan include St. Vincent's Health System & Shriners Hospitals for Children.
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Journal ArticleDOI
Treatment of rheumatoid arthritis with recombinant human interleukin‐1 receptor antagonist
Barry Bresnihan,José María Álvaro-Gracia,Mark Cobby,Michael Doherty,Zlatko Domljan,Paul Emery,George Nuki,Karel Pavelka,Rolf Rau,Blaz Rozman,Iain Watt,Bryan D. Williams,Roger Aitchison,Dorothy McCabe,Predrag Musikic +14 more
TL;DR: IL-1Ra is the first biologic agent to demonstrate a beneficial effect on the rate of joint erosion and is confirmed both the efficacy and the safety in a large cohort of patients with active and severe RA.
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Synovial tissue inflammation in early and late osteoarthritis
TL;DR: Increased mononuclear cell infiltration and overexpression of mediators of inflammation were seen in early OA, compared with late OA; these observations may have important therapeutic implications for some patients during the early evolution of OA
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Synovial tissue macrophage populations and articular damage in rheumatoid arthritis
TL;DR: The study results provided further evidence that lining layer macrophages may represent a distinct subpopulation that is of importance in this process of rheumatoid arthritis, and have implications for the development of new therapies for RA.
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EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis
Weiya Zhang,Michael Doherty,George Peat,S Ma Bierma-Zeinstra,Nigel K Arden,Barry Bresnihan,Gabriel Herrero-Beaumont,S Kirschner,Burkhard F. Leeb,L.S. Lohmander,B Mazières,Karel Pavelka,L Punzi,Alexander So,Tiraje Tuncer,Iain Watt,J. W. J. Bijlsma +16 more
TL;DR: 10 key recommendations for diagnosis of knee OA were developed using both research evidence and expert consensus and although there is no agreed reference standard, thorough clinical assessment alone can provide a confident rule-in diagnosis.
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A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience
TL;DR: This study confirms that PsA is a chronic, progressive disease in the majority of patients despite clinical improvement with current DMARD treatment, PsA results in radiological damage in up to 47% of patients at a median interval of 2 yr.