J
Jacob E. Wang
Researcher at University of Oslo
Publications - 54
Citations - 2080
Jacob E. Wang is an academic researcher from University of Oslo. The author has contributed to research in topics: Cytokine & Tumor necrosis factor alpha. The author has an hindex of 25, co-authored 54 publications receiving 2012 citations. Previous affiliations of Jacob E. Wang include Rikshospitalet–Radiumhospitalet & University of London.
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Journal ArticleDOI
Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae.
Jacob E. Wang,Adilia Warris,E. A. Ellingsen,P. F. Jørgensen,Trude Helen Flo,Terje Espevik,Rigmor Solberg,Paul E. Verweij,Ansgar O. Aasen +8 more
TL;DR: It is suggested that T cells, B cells, and monocytes are involved in the innate immune response to invasive fungal pathogens and that serum components are relevant for activation of monocytes by hyphae.
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Peptidoglycan and Lipoteichoic Acid from Staphylococcus aureus Induce Tumor Necrosis Factor Alpha, Interleukin 6 (IL-6), and IL-10 Production in Both T Cells and Monocytes in a Human Whole Blood Model
Jacob E. Wang,P. F. Jørgensen,M. Almlöf,Christoph Thiemermann,Simon J. Foster,Ansgar O. Aasen,Rigmor Solberg +6 more
TL;DR: The data indicate that circulating T cells and monocytes contribute to cytokine production in sepsis caused by gram-positive bacteria.
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Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: receptors, signal transduction, biological effects, and synergism.
Jacob E. Wang,Maria K. Dahle,Michelle C. McDonald,Simon J. Foster,Ansgar O. Aasen,Christoph Thiemermann +5 more
TL;DR: The literature underlying the current understanding of how peptidoglycan and lipoteichoic acid activate inflammatory responses will be presented, with a focus on recent advances in this field.
Journal Article
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.
Espen A. Ellingsen,Siegfried Morath,Trude H. Flo,Andra B. Schromm,Thomas Hartung,Christoph Thiemermann,Terje Espevik,Douglas T. Golenbock,Daniel Foster,Rigmor Solberg,Ansgar O. Aasen,Jacob E. Wang +11 more
TL;DR: It is proposed that LTA from S. aureus triggers the release of cytokines during staphylococcal infections, and both monocytes and T cells contribute to cytokine production induced by LTA.
Journal ArticleDOI
Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development
Sanda Sturlan,Georg Oberhuber,Britta G. Beinhauer,Brigitte Tichy,Sonja Kappel,Jacob E. Wang,Michael A. Rogy +6 more
TL;DR: No alterations in K-ras, p53, APC: and Msh2 genes suggests that other genes are involved in the development of these tumours, and Elevated TGF-beta1 plasma levels correspond to the high incidence of dysplasia and cancer.