S
Simon J. Foster
Researcher at University of Sheffield
Publications - 244
Citations - 23944
Simon J. Foster is an academic researcher from University of Sheffield. The author has contributed to research in topics: Peptidoglycan & Staphylococcus aureus. The author has an hindex of 77, co-authored 234 publications receiving 21802 citations.
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Journal ArticleDOI
Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2 IMPLICATIONS FOR CROHN′S DISEASE
Naohiro Inohara,Yasunori Ogura,Ana Fontalba,Olga Gutierrez,F. Pons,Javier Crespo,Koichi Fukase,Seiichi Inamura,Shoichi Kusumoto,Masahito Hashimoto,Simon J. Foster,Anthony P. Moran,Jose L. Fernandez-Luna,Gabriel Núñez +13 more
TL;DR: NOD2 mediates the host response to bacterial muropeptides derived from peptidoglycan, an activity that is important for protection against Crohn's disease and has implications for understanding adjuvant function and effective vaccine development.
Journal ArticleDOI
Essential Bacillus subtilis genes
Kazuto Kobayashi,Stanislav Dusko Ehrlich,Alessandra M. Albertini,G. Amati,Kasper Krogh Andersen,Maryvonne Arnaud,Kei Asai,S. Ashikaga,Stéphane Aymerich,Philippe Bessières,F. Boland,S.C. Brignell,Sierd Bron,Keigo Bunai,J. Chapuis,L.C. Christiansen,Antoine Danchin,Michel Débarbouillé,Etienne Dervyn,E. Deuerling,Kevin M. Devine,Susanne Krogh Devine,Oliver Dreesen,Jeffery Errington,Sabine Fillinger,Simon J. Foster,Yasutaro Fujita,Alessandro Galizzi,Rozenn Gardan,Caroline Eschevins,Tatsuya Fukushima,Kazuko Haga,Colin R. Harwood,Michael Hecker,D. Hosoya,Marie-Françoise Hullo,Hiroshi Kakeshita,Dimitri Karamata,Yasuhiro Kasahara,Fujio Kawamura,K. Koga,P. Koski,Ritsuko Kuwana,Daisuke Imamura,M. Ishimaru,Shu Ishikawa,I. Ishio,D. Le Coq,Anne Masson,Catherine Mauël,Rob Meima,Rafael P. Mellado,Anne Moir,Shigeki Moriya,E. Nagakawa,Hideaki Nanamiya,S. Nakai,Per Nygaard,Mitsuo Ogura,T. Ohanan,Mary O'Reilly,M. O'Rourke,Zoltán Prágai,H.M. Pooley,Georges Rapoport,J.P. Rawlins,L.A. Rivas,Carlo Rivolta,A. Sadaie,Yoshito Sadaie,Matti Sarvas,T. Sato,Hans Henrik Saxild,E. Scanlan,Wolfgang Schumann,J.F.M.L. Seegers,Junichi Sekiguchi,Agnieszka Sekowska,Simone J. Séror,M. Simon,P. Stragier,R. Studer,Hiromu Takamatsu,Teruo Tanaka,M. Takeuchi,H.B. Thomaides,Valerie Vagner,J.M. van Dijl,Kazuhito Watabe,Anil Wipat,Hiroki Yamamoto,M. Yamamoto,Y. Yamamoto,Kunio Yamane,Katsunori Yata,K. Yoshida,Hisashi Yoshikawa,Ulrich Zuber,Naotake Ogasawara +98 more
TL;DR: To estimate the minimal gene set required to sustain bacterial life in nutritious conditions, a systematic inactivation of Bacillus subtilis genes was carried out and most genes involved in the Embden–Meyerhof–Parnas pathway are essential.
Journal ArticleDOI
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.
Mathias Chamaillard,Masahito Hashimoto,Yasuo Horie,Junya Masumoto,Su Qiu,Lisa Saab,Yasunori Ogura,Akiko Kawasaki,Koichi Fukase,Shoichi Kusumoto,Miguel A. Valvano,Simon J. Foster,Tak W. Mak,Gabriel Núñez,Naohiro Inohara +14 more
TL;DR: It is reported that NOD1 mediates selective recognition of bacteria through detection of iE-DAP-containing peptidoglycan derived primarily from Gram-negative bacteria.
Journal ArticleDOI
Bacterial peptidoglycan (murein) hydrolases.
TL;DR: The current view on the regulation of autolysins and on the role of cytoplasm hydrolases in peptidoglycan recycling and induction of beta-lactamase is reviewed.
Journal ArticleDOI
sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4.
TL;DR: It is suggested that SarA is not likely to be the effector in the overall sigmaB-mediated effect on agr expression, and the levels of SarA were found to be similar in strains 8325-4 and SH1000 (8325- 4 rsbU(+)) and sigB mutant derivatives of these strains.