Jacob Fong

TL;DR: The ability of the monocytes from specifically immunized rabbits to retard the growth of virulent Brucella was demonstrated, not as an all-or-none phenomenon, but in the light of the unrestricted bacterial multiplication which occurs in monocyte from normal animals.

TL;DR: Studies of the conditions necessary for maintenance of constant cell populations in vitro in the Mackaness type of culture chamber have indicated the importance of preliminary trypsinization of cells and the beneficial effect of 40 per cent rabbit serum in Tyrode's solution.

TL;DR: It was demonstrated that immune serum (anti-BCG) protected immune cells against H37Rv but not against O.T. and P.P.D, and the protection of immune cells by heterologous antisera ( anti-Salmonella and anti-ovalbumin) as well as by homologous anti- BCG against the degenerative effects of H 37Rv indicated a non-specificity in action of serum factors.

TL;DR: The various cellular components of immune rabbit histiocytes have been analyzed for their ability to induce cellular resistance in normal animals and shown that the nuclear and mitochondrial fractions were inactive and that the microsomal and ribosomal fractions were active.

TL;DR: Experiments to establish the mechanism of passive transfer of cellular resistance showed that there was no active induction of resistance in recipients through transfer of bacillary antigens contained in immune histiocytes; in fact, the results of serial passive transfers with immune Histiocytes suggested an active replication of the "cell resistance factor."