J
Jacob M. Waugh
Researcher at Stanford University
Publications - 62
Citations - 2669
Jacob M. Waugh is an academic researcher from Stanford University. The author has contributed to research in topics: Neointima & Restenosis. The author has an hindex of 26, co-authored 62 publications receiving 2623 citations. Previous affiliations of Jacob M. Waugh include Baylor College of Medicine.
Papers
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Journal ArticleDOI
Vascular endothelial growth factor enhances atherosclerotic plaque progression.
Francesca L. Celletti,Jacob M. Waugh,Philippe Amabile,Andrea Brendolan,Paul R. Hilfiker,Michael D. Dake +5 more
TL;DR: Vascular endothelial growth factor (VEGF) significantly increased macrophage levels in bone marrow and peripheral blood and increased plaque area 5-, 14- and 4-fold compared with controls at weeks 1, 2 and 3, respectively.
Journal ArticleDOI
Increased free fat-graft survival with the long-term, local delivery of insulin, insulin-like growth factor-I, and basic fibroblast growth factor by PLGA/PEG microspheres
Eser Yuksel,Adam B. Weinfeld,Robert Cleek,Susann Wamsley,John N. Jensen,Sean Boutros,Jacob M. Waugh,Saleh M. Shenaq,Melvin Spira +8 more
TL;DR: Long‐term, local delivery of growth factors with PLGA/PEG microspheres has the potential to increase fat‐graft survival rates and the type of growth factor delivered may influence the cellular/stromal composition of the grafted tissue.
Patent
Drug delivery platform
TL;DR: A stent-based drug delivery system is described in this paper, where a biological agent of interest is entrapped within a matrix, which is loaded into channels on the surface of a stent.
Journal ArticleDOI
Liver tissue engineering at extrahepatic sites in mice as a potential new therapy for genetic liver diseases.
Kazuo Ohashi,Kazuo Ohashi,Jacob M. Waugh,Michael D. Dake,Takashi Yokoyama,Hiroyuki Kuge,Yoshiyuki Nakajima,Masaki Yamanouchi,Hiroyuki Naka,Akira Yoshioka,Mark A. Kay +10 more
TL;DR: These studies indicate that liver tissues can be engineered and maintained at extrahepatic sites, retain their capacity for regeneration in vivo, and used to successfully treat genetic disorders.
Journal ArticleDOI
De novo adipose tissue generation through long-term, local delivery of insulin and insulin-like growth factor-1 by PLGA/PEG microspheres in an in vivo rat model : A novel concept and capability
Eser Yuksel,Adam B. Weinfeld,Robert Cleek,Jacob M. Waugh,John N. Jensen,Sean Boutros,Saleh M. Shenaq,Melvin Spira +7 more
TL;DR: The long‐term release of proteins from PLGA/PEG microspheres up to 4 weeks is confirmed and the potential of long‐ term local insulin and IGF‐1 to induce adipogenic differentiation to mature lipid‐containing adipocytes from nonadipocyte cell pools in vivo is demonstrated at 4 weeks.