J
Jacqueline A. Upcroft
Researcher at QIMR Berghofer Medical Research Institute
Publications - 68
Citations - 4435
Jacqueline A. Upcroft is an academic researcher from QIMR Berghofer Medical Research Institute. The author has contributed to research in topics: Giardia & Trichomonas vaginalis. The author has an hindex of 34, co-authored 68 publications receiving 4229 citations. Previous affiliations of Jacqueline A. Upcroft include University of Queensland.
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Journal ArticleDOI
Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis
Jane M. Carlton,Robert P. Hirt,Joana C. Silva,Arthur L. Delcher,Michael C. Schatz,Qi Zhao,Jennifer R. Wortman,Shelby L. Bidwell,U. Cecilia M. Alsmark,Sébastien Besteiro,Thomas Sicheritz-Pontén,Christophe Noël,Joel B. Dacks,Peter G. Foster,Cedric Simillion,Yves Van de Peer,Diego Miranda-Saavedra,Geoffrey J. Barton,Gareth D. Westrop,Sylke Müller,Daniele Dessì,Pier Luigi Fiori,Qinghu Ren,Ian T. Paulsen,Hanbang Zhang,Felix D. Bastida-Corcuera,Augusto Simoes-Barbosa,Mark T. Brown,Richard D. Hayes,Mandira Mukherjee,Cheryl Y. M. Okumura,Rachel E. Schneider,Alias J. Smith,Stepanka Vanacova,Maria Villalvazo,Brian J. Haas,Mihaela Pertea,Tamara Feldblyum,T. Utterback,Chung-Li Shu,Kazutoyo Osoegawa,Pieter J. de Jong,Ivan Hrdy,Lenka Horváthová,Zuzana Zubáčová,Pavel Dolezal,Shehre-Banoo Malik,John M. Logsdon,Katrin Henze,Arti Gupta,Ching C. Wang,R. L. Dunne,Jacqueline A. Upcroft,Peter Upcroft,Owen White,Steven L. Salzberg,Petrus Tang,Cheng-Hsun Chiu,Ying-Shiung Lee,T. Martin Embley,Graham H. Coombs,Jeremy C. Mottram,Jan Tachezy,Claire M. Fraser-Liggett,Patricia J. Johnson +64 more
TL;DR: The genome sequence of the protist Trichomonas vaginalis predicts previously unknown functions for the hydrogenosome, which support a common evolutionary origin of this unusual organelle with mitochondria.
Journal ArticleDOI
Drug targets and mechanisms of resistance in the anaerobic protozoa
TL;DR: The review examines the value of investigating both clinical and laboratory-induced syngeneic drug-resistant isolates and dissection of the complementary data obtained, as well as thevalue of studies of the epidemiology of resistance.
Journal ArticleDOI
Drug resistance in the sexually transmitted protozoan Trichomonas vaginalis
TL;DR: Drug resistance incidence in T. vaginalis appears to be on the increase and improved surveillance of treatment failures is urged, with cross-resistance among the family of 5-nitroimidazole drugs common.
Journal ArticleDOI
A rhoptry antigen of Plasmodium falciparum contains conserved and variable epitopes recognized by inhibitory monoclonal antibodies.
TL;DR: Four monoclonal antibodies produced against Plasmodium falciparum recognize an antigen in merozoites that is localized in rhoptries, as judged by a punctate, double dot fluorescence pattern.
Journal ArticleDOI
Involvement of superoxide dismutase and pyruvate:ferredoxin oxidoreductase in mechanisms of metronidazole resistance in Entamoeba histolytica.
Nirma A. Samarawickrema,David M. Brown,Jacqueline A. Upcroft,Nitaya Thammapalerd,Peter Upcroft +4 more
TL;DR: Resistance to metronidazole resistance has been induced in an axenic strain of Entamoeba histolytica following continuous exposure to steadily increasing drug concentrations and a marked increase in superoxide dismutase activity was detected.