Lenka Horváthová

TL;DR: The genome sequence of the protist Trichomonas vaginalis predicts previously unknown functions for the hydrogenosome, which support a common evolutionary origin of this unusual organelle with mitochondria.

TL;DR: The computational and experimental/functional analyses reveal that the divergent processing peptidases of Giardia mitosomes and Trichomonas hydrogenosomes evolved from the same ancestral heterodimeric α/βMPP metallopeptidase as did the classic mitochondrial enzyme.

TL;DR: In this article, the role of iron in T. vaginalis gene expression and genome evolution was investigated using an oligonucleotide microarray for T. vaginais and by comparative EST sequencing of cDNA libraries derived from trichomonads cultivated under iron-rich (+Fe) and iron-restricted (� Fe) conditions.

TL;DR: This finding indicates a stringent regulation of differentially expressed multiple gene copies in response to changes in the availability of exogenous iron, which is also one of the mechanisms involved in immunity.

TL;DR: The type 2 secretion system (T2SS) is present in some Gram-negative eubacteria and used to secrete proteins across the outer membrane as discussed by the authors, and at least some of them are present in mitochondria, and their behaviour in biochemical assays is consistent with the presence of a mitochondrial T2SS-derived system.