J
Jacques H. Abraini
Researcher at University of Caen Lower Normandy
Publications - 95
Citations - 2366
Jacques H. Abraini is an academic researcher from University of Caen Lower Normandy. The author has contributed to research in topics: Nucleus accumbens & Agonist. The author has an hindex of 27, co-authored 95 publications receiving 2209 citations. Previous affiliations of Jacques H. Abraini include Laval University & Hoffmann-La Roche.
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Dopamine-glutamate reciprocal modulation of release and motor responses in the rat caudate-putamen and nucleus accumbens of "intact" animals.
TL;DR: The available data demonstrate that dopamine and glutamate do not uniformly interact to modulate each others' release and postsynaptic modulation of striatal output neurons.
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Reduction of Ischemic Brain Damage by Nitrous Oxide and Xenon
Hélène N. David,Frédéric Léveillé,Laurent Chazalviel,Eric T. MacKenzie,Alain Buisson,Marc Lemaire,Jacques H. Abraini,Jacques H. Abraini +7 more
TL;DR: In this paper, the authors investigated whether nitrous oxide or xenon, which are gaseous anesthetics with a remarkably safe clinical profile that have been recently demonstrated as effective inhibitors of the NMDA receptor, may reduce the following: (1) ischemia-induced brain damage in vivo, when given after occlusion of the middle cerebral artery (MCAO), a condition needed to make these potentially neuroprotective agents therapeutically valuable; or (2) NMDA-induced Ca2+ influx in cortical cell cultures, a major critical event involved in exc
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Psychophysiological reactions in humans during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture
TL;DR: The hypothesis that hydrogen can alleviate some of the symptoms of the high-pressure nervous syndrome and can constitute a useful gas for commercial diving is supported, as it decreases the density of the breathing mixture and therefore improves the living conditions, work, and comfort of the divers.
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Neuroprotective effects of xenon: a therapeutic window of opportunity in rats subjected to transient cerebral ischemia
Hélène N. David,Benoit Haelewyn,Christophe Rouillon,Myriam Lecoq,Laurent Chazalviel,Gabriela Apiou,Jean-Jacques Risso,Marc Lemaire,Jacques H. Abraini +8 more
TL;DR: It is shown that xenon, administered at subanesthetic doses, offers global neuroprotection from reduction of neurotransmitter release induced by ischemia, a critical event known to be involved in excitotoxicity, to reduction of subsequent cell injury and neuronal death.
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Relationships between mood states and performances in reaction time, psychomotor ability, and mental efficiency during a 31-day gradual decompression in a hypobaric chamber from sea level to 8848 m equivalent altitude.
TL;DR: Data indicate, in agreement with previous studies, that anxiety may favour, or at least not alter, the processes of information of relatively simple tasks, such as reaction time, and further suggest that adverse changes in moods could modulate performance negatively.