J
Jae-Won Lee
Researcher at Korea Research Institute of Bioscience and Biotechnology
Publications - 52
Citations - 776
Jae-Won Lee is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: Proinflammatory cytokine & Tumor necrosis factor alpha. The author has an hindex of 14, co-authored 44 publications receiving 538 citations. Previous affiliations of Jae-Won Lee include Food and Drug Administration.
Papers
More filters
Journal ArticleDOI
Anti-inflammatory effects of linalool on ovalbumin-induced pulmonary inflammation.
Min-Gu Kim,Seong-Man Kim,Jae-Hong Min,Ok-Kyoung Kwon,Mi-Hyeong Park,Ji-Won Park,Hye In Ahn,Jeong-Yeon Hwang,Sei-Raying Oh,Jae-Won Lee,Kyung-Seop Ahn +10 more
TL;DR: Linalool effectively exerts a protective role in OVA-induced airway inflammation and mucus hypersecretion, and its protective effects are closely related to the downregulation of inflammatory mediators and MAPKs/NF-κB signaling.
Journal ArticleDOI
Community patterning and identification of predominant factors in algal bloom in Daechung Reservoir (Korea) using artificial neural networks
TL;DR: The water temperature, total particulate nitrogen, daily irradiance, and total nitrogen were highlighted as the four most important environmental variables predicting cyanobacterial abundance, yet quite different environmental variables were found to affect the chlorophyll-a concentration.
Journal ArticleDOI
Molecular Mechanism of Tetrabromobisphenol A (TBBPA)-induced Target Organ Toxicity in Sprague-Dawley Male Rats
Jae Seok Choi,Young Jun Lee,Tae Hyung Kim,Hyun Jung Lim,Mee Young Ahn,Seung Jun Kwack,Tae Seok Kang,Kui Lea Park,Jae-Won Lee,Nam Deuk Kim,Tae Cheon Jeong,Sang Geum Kim,Hye Gwang Jeong,Byung Mu Lee,Hyung Sik Kim +14 more
TL;DR: Results indicate that repeated exposure to T BBPA induces drug-metabolising enzymes in rats through the CAR signaling pathway, and suggest that TBBPA-induced target organ toxicity may be due to ROS produced by metabolism of TBB PA in Sprague- Dawley rats.
Journal ArticleDOI
Asiatic acid inhibits pulmonary inflammation induced by cigarette smoke.
Jae-Won Lee,Hyun Ah Park,Ok-Kyoung Kwon,Yin-Gi Jang,Ju Yeong Kim,Bo Kyung Choi,Hee Jae Lee,Sang Woo Lee,Jin-Hyub Paik,Sei-Ryang Oh,Kyung-Seop Ahn,Hyun-Jun Lee +11 more
TL;DR: The findings indicate that AA effectively inhibits pulmonary inflammatory response, which is an important process in the development of chronic obstructive pulmonary disease (COPD) via suppression of inflammatory mediators and induction of HO-1.
Journal ArticleDOI
Protective effects of neem (Azadirachta indica A. Juss.) leaf extract against cigarette smoke- and lipopolysaccharide-induced pulmonary inflammation.
Jae-Won Lee,Hyung Won Ryu,So-Yeon Park,Hyun Ah Park,Ok-Kyoung Kwon,Heung Joo Yuk,Krishna Kumar Shrestha,Min-Woo Park,Jung Hee Kim,Sang Woo Lee,Sei-Ryang Oh,Kyung-Seop Ahn +11 more
TL;DR: Treatment with neem leaf extract (NLE) against cigarette smoke and lipopolysaccharide-induced pulmonary inflammation suggests that NLE has potential in the treatment of chronic obstructive pulmonary disease.