J
Jahnvi Purwar
Researcher at University of Utah
Publications - 3
Citations - 1496
Jahnvi Purwar is an academic researcher from University of Utah. The author has contributed to research in topics: Genomic imprinting & Epigenetics. The author has an hindex of 3, co-authored 3 publications receiving 1370 citations. Previous affiliations of Jahnvi Purwar include Brigham Young University & Huntsman Cancer Institute.
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Distinctive chromatin in human sperm packages genes for embryo development
Saher Sue Hammoud,David A. Nix,Haiying Zhang,Jahnvi Purwar,Douglas T. Carrell,Bradley R. Cairns +5 more
TL;DR: It is shown that the retained nucleosomes are significantly enriched at loci of developmental importance, including imprinted gene clusters, microRNA clusters, HOX genes clusters, and the promoters of stand-alone developmental transcription and signalling factors.
Journal ArticleDOI
Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility
Saher Sue Hammoud,Jahnvi Purwar,Christian Pflueger,Bradley R. Cairns,Bradley R. Cairns,Douglas T. Carrell +5 more
TL;DR: Patients with male factor infertility had significantly increased methylation alteration at six of seven imprinted loci tested, with differences in significance observed between oligozoospermic and abnormal protamine patients, suggesting that risk of transmission of epigenetic alterations may be different with diagnoses.
Journal ArticleDOI
The GNUMAP algorithm
Nathan L. Clement,Quinn Snell,Mark J. Clement,Peter C. Hollenhorst,Jahnvi Purwar,Barbara J. Graves,Bradley R. Cairns,W. Evan Johnson,W. Evan Johnson +8 more
TL;DR: GNUMAP (Genomic Next-generation Universal MAPper), a program capable of overcoming two major obstacles in the mapping of reads from next-generation sequencing runs, is presented, which has been created an algorithm that probabilistically maps reads to repeat regions in the genome on a quantitative basis.