James A. Bonner

TL;DR: Combined modality approaches, such as radiotherapy administered concomitantly with the initiation of chemotherapy, induction chemotherapy followed by radiotherapy administer during the subsequent courses of chemotherapy), sequential chemotherapy and radiotherapy, and courses of radiotherapy split between cycles of chemotherapy are important for improving survival in patients with SCLC.

TL;DR: Atypical histologic findings in patients who had undergone complete resection of bronchial carcinoid tumors were associated with increased local-regional disease recurrence and decreased survival compared with recurrences and survival in patients with typical Histologic findings.

TL;DR: These studies revealed that the greater anti-proliferative effects and increased cytotoxicity of cetuximab in the STAT3-2.17 cells, may be a result ofSTAT3-mediated effects on cellular apoptosis and DNA damage.

TL;DR: Patients with head and neck carcinomas are being evaluated in phase III studies exploring the combination of IMC-C225 and radiation as well as the combination with radiotherapy or chemotherapy and cisplatin in locally advanced and recurrent disease.

TL;DR: Patients with high MARCKS expressing tumors of the proneural molecular subtype of GBM had significantly increased survival rates, and this effect was most pronounced in tumors with unmethylated O6-methylguanine DNA methyltransferase (MGMT) promoters, a traditionally poor prognostic factor.