J
James A. Profitt
Researcher at Siemens
Publications - 17
Citations - 329
James A. Profitt is an academic researcher from Siemens. The author has contributed to research in topics: Analyte & Inlet. The author has an hindex of 8, co-authored 17 publications receiving 327 citations. Previous affiliations of James A. Profitt include Hatch Ltd & Bayer Corporation.
Papers
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Journal ArticleDOI
Au nanoparticle conjugation for impedance and capacitance signal amplification in biosensors.
TL;DR: A change in the electrochemical impedance signal upon binding to goat anti-fluorescein conjugated with Au nanoparticles can be attributed to the much higher electrochemical activity of Au surfaces relative to the underlying organic layer.
Patent
Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
TL;DR: In this paper, a microliter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces, which defines the amount of said sample to be analyzed in subsequent steps.
Journal ArticleDOI
High-sensitivity dye binding assay for albumin in urine.
TL;DR: A system that minimized nonspecific binding by the dye through the use of polymethyl vinyl ethers and bis‐(heptapropylene glycol) carbonate showed a greater chemical specificity for albumin when compared to most other proteins.
Patent
Method for uniform application of fluid into a reactive reagent area
Michael J. Pugia,James A. Profitt,Hai-Hang Kuo,Gert Blankenstein,Ralf-Peter Peters,Lloyd S. Schulman +5 more
TL;DR: In this article, structural features in areas containing dry supported reagents are used to guide the flow of a sample over the area in a predetermined uniform manner and facilitate the purging of air.
Patent
Method and apparatus for entry and storage of specimens into a microfluidic device
TL;DR: In this paper, a microfluidic device for analyzing biological samples is provided with a sample inlet section including an inlet port, a capillary passageway communicating with the inlet ports and with an inner chamber.