J
James Cohen
Researcher at King's College London
Publications - 57
Citations - 6073
James Cohen is an academic researcher from King's College London. The author has contributed to research in topics: Neurite & Dorsal root ganglion. The author has an hindex of 37, co-authored 57 publications receiving 5961 citations. Previous affiliations of James Cohen include Guy's Hospital & Open University.
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Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics
TL;DR: Two types of glial fibrillary acidic protein-positive (GFAP+) astrocytes were found in cultures of developing rat optic nerve and these ligands cannot be used on their own as neuron- specific markers in central nervous system cultures.
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Glia are a unique substrate for the in vitro growth of central nervous system neurons
TL;DR: The findings suggest that the interaction of axons with the non-neuronal milieu through which they grow may play an important role in regulating fasciculation, a process which has generally been treated as due primarily to axon-axon interactions.
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Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse
TL;DR: Immunohistochemical studies show that the distribution of the extracellular matrix glycoprotein laminin is not significantly different in the cephalic region of Sey/Sey versus Sey/+ or +/+ embryos.
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Safety, immunogenicity, and efficacy of a recombinantly produced Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccine.
Daniel M. Gordon,T. W. McGovern,Urszula Krzych,James Cohen,Imogene Schneider,R. LaChance,D. G. Heppner,G. Yuan,Michael R. Hollingdale,Moncef Mohamed Slaoui,Pierre Hauser,P. Voet,Jerald C. Sadoff,W. R. Ballou +13 more
TL;DR: Twenty malaria-naive volunteers received a recombinant Plasmodium falciparum malaria vaccine (RTS,S) containing 19 NANP repeats and the carboxy terminus of the circumsporozoite (CS) antigen coexpressed in yeast with hepatitis B surface antigen and MPL enhanced CS antibody levels.
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Neurite outgrowth in response to transfected N-CAM changes during development and is modulated by polysialic acid.
TL;DR: The data provide substantive evidence for a homophilic binding mechanism directly mediating N-CAM-dependent neurite outgrowth, and suggest that changes in polysialic acid expression on neuronal N-cAM may modulate N- CAM- dependent axonal growth during development.