J
James D. Hayhurst
Researcher at European Bioinformatics Institute
Publications - 26
Citations - 5465
James D. Hayhurst is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: Genome-wide association study & Biology. The author has an hindex of 9, co-authored 20 publications receiving 3349 citations. Previous affiliations of James D. Hayhurst include Anthony Nolan & Royal Free Hospital.
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Journal ArticleDOI
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019.
Annalisa Buniello,Jacqueline A. L. MacArthur,Maria Cerezo,Laura W. Harris,James D. Hayhurst,Cinzia Malangone,Aoife McMahon,Joannella Morales,Edward Mountjoy,Edward Mountjoy,Elliot Sollis,Daniel Suveges,Olga Vrousgou,Patricia L. Whetzel,M. Ridwan Amode,Jose A. Guillen,Harpreet Singh Riat,Stephen J. Trevanion,Peggy Hall,Heather Junkins,Paul Flicek,Tony Burdett,Lucia A. Hindorff,Fiona Cunningham,Helen Parkinson +24 more
TL;DR: Improved data access is improved with the release of a new RESTful API to support high-throughput programmatic access, an improved web interface and a new summary statistics database.
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The IPD and IMGT/HLA database: allele variant databases
James Robinson,Jason A. Halliwell,James D. Hayhurst,Paul Flicek,Peter Parham,Steven G.E. Marsh +5 more
TL;DR: The Immuno Polymorphism Database was developed to provide a centralized system for the study of polymorphism in genes of the immune system and continues to develop with new tools being added to address scientific developments, and to address user feedback and requests.
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Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics.
Maya Ghoussaini,Edward Mountjoy,Miguel Carmona,Gareth Peat,Ellen M. Schmidt,Andrew Hercules,Luca Fumis,Alfredo Miranda,Denise Carvalho-Silva,Annalisa Buniello,Tony Burdett,James D. Hayhurst,Jarrod Baker,Javier Ferrer,Asier Gonzalez-Uriarte,Simon Jupp,Mohd Anisul Karim,Gautier Koscielny,Sandra Machlitt-Northen,Cinzia Malangone,Zoë May Pendlington,Paola Roncaglia,Daniel Suveges,Daniel Wright,Olga Vrousgou,Eliseo Papa,Helen Parkinson,Jacqueline A. L. MacArthur,John A. Todd,Jeffrey C. Barrett,Jeremy Schwartzentruber,David G. Hulcoop,David Ochoa,Ellen M. McDonagh,Ellen M. McDonagh,Ian Dunham,Ian Dunham +36 more
TL;DR: Open Targets Genetics offers tools that enable users to prioritise causal variants and genes at disease-associated loci and access systematic cross-disease and disease-molecular trait colocalization analysis across 92 cell types and tissues including the eQTL Catalogue.
Journal ArticleDOI
An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci.
Edward Mountjoy,Ellen M. Schmidt,Miguel Carmona,Jeremy Schwartzentruber,Jeremy Schwartzentruber,Gareth Peat,Alfredo Miranda,Luca Fumis,James D. Hayhurst,Annalisa Buniello,Mohd Anisul Karim,Daniel Wright,Andrew Hercules,Eliseo Papa,Eric B. Fauman,Jeffrey C. Barrett,John A. Todd,David Ochoa,Ian Dunham,Ian Dunham,Maya Ghoussaini +20 more
TL;DR: Open Targets Genetics as discussed by the authors is a community resource that provides systematic fine mapping at human GWAS loci, enabling users to prioritize genes at disease-associated regions and assess their potential as drug targets.
Journal ArticleDOI
A compendium of uniformly processed human gene expression and splicing quantitative trait loci.
Nurlan Kerimov,James D. Hayhurst,Kateryna Peikova,Jonathan R. Manning,Peter Walter,Liis Kolberg,Marija Samoviča,Manoj Pandian Sakthivel,Ivan Kuzmin,Stephen J. Trevanion,Tony Burdett,Simon Jupp,Helen Parkinson,Irene Papatheodorou,Andrew D. Yates,Daniel R. Zerbino,Kaur Alasoo +16 more
TL;DR: The eQTL Catalogue as discussed by the authors is a set of gene expression quantitative trait locus (eQTL) studies published their summary statistics, which can be used to gain insight into complex human traits by downstream analyses, such as fine mapping and co-localization.