E
Edward Mountjoy
Researcher at Wellcome Trust Sanger Institute
Publications - 14
Citations - 4274
Edward Mountjoy is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Genome-wide association study & Identification (biology). The author has an hindex of 10, co-authored 13 publications receiving 2111 citations. Previous affiliations of Edward Mountjoy include University of Oxford & University of Bristol.
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Journal ArticleDOI
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019.
Annalisa Buniello,Jacqueline A. L. MacArthur,Maria Cerezo,Laura W. Harris,James D. Hayhurst,Cinzia Malangone,Aoife McMahon,Joannella Morales,Edward Mountjoy,Edward Mountjoy,Elliot Sollis,Daniel Suveges,Olga Vrousgou,Patricia L. Whetzel,M. Ridwan Amode,Jose A. Guillen,Harpreet Singh Riat,Stephen J. Trevanion,Peggy Hall,Heather Junkins,Paul Flicek,Tony Burdett,Lucia A. Hindorff,Fiona Cunningham,Helen Parkinson +24 more
TL;DR: Improved data access is improved with the release of a new RESTful API to support high-throughput programmatic access, an improved web interface and a new summary statistics database.
Journal ArticleDOI
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
Manuel A. R. Ferreira,Judith M. Vonk,Hansjörg Baurecht,Ingo Marenholz,Ingo Marenholz,Chao Tian,Joshua D. Hoffman,Quinta Helmer,Annika Tillander,Vilhelmina Ullemar,Jenny van Dongen,Yi Lu,Franz Rüschendorf,Jorge Esparza-Gordillo,Jorge Esparza-Gordillo,Jorge Esparza-Gordillo,Chris W. Medway,Edward Mountjoy,Kimberley Burrows,Oliver Hummel,Sarah Grosche,Sarah Grosche,Ben Michael Brumpton,Ben Michael Brumpton,John S. Witte,Jouke-Jan Hottenga,Gonneke Willemsen,Jie Zheng,Elke Rodriguez,Melanie Hotze,Andre Franke,Joana A. Revez,Jonathan Beesley,Melanie C. Matheson,Shyamali C. Dharmage,L. Bain,Lars G. Fritsche,Maiken Elvestad Gabrielsen,Brunilda Balliu,Jonas B. Nielsen,Wei Zhou,Kristian Hveem,Arnulf Langhammer,Oddgeir L. Holmen,Mari Løset,Gonçalo R. Abecasis,Gonçalo R. Abecasis,Cristen J. Willer,Andreas Arnold,Georg Homuth,Carsten Oliver Schmidt,Philip J. Thompson,Nicholas G. Martin,David L. Duffy,Natalija Novak,Holger Schulz,Stefan Karrasch,Christian Gieger,Konstantin Strauch,Ronald B. Melles,David A. Hinds,Norbert Hubner,Stephan Weidinger,Patrik K. E. Magnusson,Rick Jansen,Eric Jorgenson,Young-Ae Lee,Young-Ae Lee,Dorret I. Boomsma,Catarina Almqvist,Catarina Almqvist,Robert Karlsson,Gerard H. Koppelman,Lavinia Paternoster +73 more
TL;DR: A genome-wide association study of a broad allergic disease phenotype that considers the presence of any one of these three diseases identified 136 independent risk variants, including 73 not previously reported, which implicate 132 nearby genes in allergic disease pathophysiology.
Journal ArticleDOI
Open Targets Platform: supporting systematic drug-target identification and prioritisation.
David Ochoa,Andrew Hercules,Miguel Carmona,Daniel Suveges,Asier Gonzalez-Uriarte,Cinzia Malangone,Alfredo Miranda,Luca Fumis,Denise Carvalho-Silva,Michaela Spitzer,Jarrod Baker,Javier Ferrer,Arwa Bin Raies,Olesya Razuvayevskaya,Adam Faulconbridge,Eirini Petsalaki,Prudence Mutowo,Sandra Machlitt-Northen,Gareth Peat,Elaine McAuley,Chuang Kee Ong,Edward Mountjoy,Maya Ghoussaini,Andrea Pierleoni,Eliseo Papa,Miguel Pignatelli,Gautier Koscielny,Mohd Anisul Karim,Jeremy Schwartzentruber,David G. Hulcoop,Ian Dunham,Ian Dunham,Ellen M. McDonagh +32 more
TL;DR: To aid the prioritisation of targets and inform on the potential impact of modulating a given target, evaluation of post-marketing adverse drug reactions and new curated information on target tractability and safety are added.
Journal ArticleDOI
Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics.
Maya Ghoussaini,Edward Mountjoy,Miguel Carmona,Gareth Peat,Ellen M. Schmidt,Andrew Hercules,Luca Fumis,Alfredo Miranda,Denise Carvalho-Silva,Annalisa Buniello,Tony Burdett,James D. Hayhurst,Jarrod Baker,Javier Ferrer,Asier Gonzalez-Uriarte,Simon Jupp,Mohd Anisul Karim,Gautier Koscielny,Sandra Machlitt-Northen,Cinzia Malangone,Zoë May Pendlington,Paola Roncaglia,Daniel Suveges,Daniel Wright,Olga Vrousgou,Eliseo Papa,Helen Parkinson,Jacqueline A. L. MacArthur,John A. Todd,Jeffrey C. Barrett,Jeremy Schwartzentruber,David G. Hulcoop,David Ochoa,Ellen M. McDonagh,Ellen M. McDonagh,Ian Dunham,Ian Dunham +36 more
TL;DR: Open Targets Genetics offers tools that enable users to prioritise causal variants and genes at disease-associated loci and access systematic cross-disease and disease-molecular trait colocalization analysis across 92 cell types and tissues including the eQTL Catalogue.
Journal ArticleDOI
Education and myopia: assessing the direction of causality by mendelian randomisation
Edward Mountjoy,Neil M Davies,Denis Plotnikov,George Davey Smith,Santiago Rodriguez,Cathy Williams,Jeremy A. Guggenheim,Denize Atan +7 more
TL;DR: This study shows that exposure to more years in education contributes to the rising prevalence of myopia, and increasing the length of time spent in education may inadvertently increase the prevalence ofMyopia and potential future visual disability.