Liis Kolberg

TL;DR: G:Profiler is now capable of analysing data from any organism, including vertebrates, plants, fungi, insects and parasites, and the 2019 update introduces an extensive technical rewrite making the services faster and more flexible.

TL;DR: The 2016 update of g:Profiler introduces several novel features, including transcription factor binding site predictions, Mendelian disease annotations, information about protein expression and complexes and gene mappings of human genetic polymorphisms.

TL;DR: The accompanying R package, gprofiler2, developed to facilitate programmatic access to g:Profiler computations and databases via REST API, provides an easy-to-use functionality that enables researchers to incorporate functional enrichment analysis into automated analysis pipelines written in R.

TL;DR: The eQTL Catalogue as discussed by the authors is a set of gene expression quantitative trait locus (eQTL) studies published their summary statistics, which can be used to gain insight into complex human traits by downstream analyses, such as fine mapping and co-localization.

TL;DR: The eQTL Catalogue is presented, a resource which contains quality controlled, uniformly recomputed QTLs from 21 eQtl studies, and it is found that for matching cell types and tissues, the eZTL effect sizes are highly reproducible between studies, enabling the integrative analysis of these data.