J
James E. Dennis
Researcher at Baylor College of Medicine
Publications - 129
Citations - 13039
James E. Dennis is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Mesenchymal stem cell & Cartilage. The author has an hindex of 49, co-authored 126 publications receiving 12392 citations. Previous affiliations of James E. Dennis include Case Western Reserve University & University of Chile.
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Journal ArticleDOI
Mesenchymal stem cells as trophic mediators.
Arnold I. Caplan,James E. Dennis +1 more
TL;DR: Several studies which tested the use of MSCs in models of infarct (injured heart), stroke (brain), or meniscus regeneration models are reviewed within the context of M SC‐mediated trophic effects in tissue repair.
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The Dynamic in vivo Distribution of Bone Marrow-Derived Mesenchymal Stem Cells after Infusion
TL;DR: Rat marrow-derived MSCs were ex vivo culture-expanded, labeled with 111In-oxine, and infused into syngeneic rats via intra-artery, intravenous and intraperitoneal cavity infusions, indicating multiple homing sites for injected M SCs and that the distribution of MSCS can be influenced by administration of vasodilator.
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Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation
Basabi Maitra,Emese Szekely,K Gjini,Mary J. Laughlin,James E. Dennis,Stephen E. Haynesworth,Omer N. Koc +6 more
TL;DR: Preclinical data suggest that unrelated, human bone marrow-derived, culture-expanded MSCs may improve the outcome of allogeneic transplantation by promoting hematopoietic engraftment and limiting GVHD and their therapeutic potential should be tested in clinic.
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A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse
James E. Dennis,Anita P. Merriam,Amad Awadallah,Jung U. Yoo,Brian Johnstone,Arnold I. Caplan +5 more
TL;DR: The bone marrow–derived clone BMC9 has the potential to express each of the four mesenchymal characteristics tested, while brain fibroblasts, tested under identical conditions, did not exhibit any of these four MesenchymAl characteristics.
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Hyaluronic acid-based polymers as cell carriers for tissue-engineered repair of bone and cartilage.
TL;DR: The hyaluronic acid‐based delivery vehicles are superior to porous calcium phosphate ceramic with respect to the number of cells loaded per unit volume of implant, and HYAFF 11 sponges are inferior to the ceramics with regard to the amount of bone and cartilage formed.