Jizong Gao

TL;DR: A new, intrinsically pluripotent, CD45-negative population from human cord blood, termed unrestricted somatic stem cells (USSCs) is described, which grows adherently and can be expanded to 1015 cells without losing pluripotency.

TL;DR: Rat marrow-derived MSCs were ex vivo culture-expanded, labeled with 111In-oxine, and infused into syngeneic rats via intra-artery, intravenous and intraperitoneal cavity infusions, indicating multiple homing sites for injected M SCs and that the distribution of MSCS can be influenced by administration of vasodilator.

TL;DR: The data suggest that the construction of a tissue-engineered composite osteochondral graft is possible with MSCs and different biomaterials and bioactive factors that support either chondrogenic or osteogenic differentiation.

TL;DR: It is the hypothesis that hyaluronan-based scaffolds are superior to synthetic scaffolds because they provide biological cues and appear to allow faster cell infiltration leading to faster tissue formation.

TL;DR: The fibronectin-coated hyaluronan-based scaffold appears to organize the natural response and facilitate the integration of the neo-cartilage with the adjacent tissue in osteochondral repair.