J
James G. Herndon
Researcher at Yerkes National Primate Research Center
Publications - 109
Citations - 6760
James G. Herndon is an academic researcher from Yerkes National Primate Research Center. The author has contributed to research in topics: Modified vaccinia Ankara & Cognition. The author has an hindex of 41, co-authored 108 publications receiving 6440 citations. Previous affiliations of James G. Herndon include Boston University & Vaccine Research Center.
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Journal ArticleDOI
Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.
Rama Rao Amara,Francois Villinger,John D. Altman,Shari L. Lydy,Shawn P. O'Neil,Silvija I. Staprans,David C. Montefiori,Yan Xu,James G. Herndon,Linda S. Wyatt,Maria Angelito Candido,Natalia Kozyr,Patricia L. Earl,James M. Smith,Hak-Ling Ma,Hak-Ling Ma,Bennett D. Grimm,Michael L. Hulsey,Joseph I. Miller,Harold M. McClure,Janet M. McNicholl,Bernard Moss,Harriet L. Robinson +22 more
TL;DR: DNA priming followed by a recombinant modified vaccinia Ankara (rMVA) booster controlled a highly pathogenic immunodeficiency virus challenge in a rhesus macaque model, providing hope that a relatively simple multiprotein DNA/MVA vaccine can help to control the acquired immune deficiency syndrome epidemic.
Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine
Rama Rao Amara,Francois Villinger,John D. Altman,Shari L. Lydy,Shari L. Lydy,Shawn P. O'Neil,Shawn P. O'Neil,Silvija I. Staprans,David C. Montefiori,Yan Xu,James G. Herndon,Linda S. Wyatt,Maria Angelito Candido,Natalia L. Kozyr,Patricia L. Earl,James M. Smith,James M. Smith,Hak-Ling Ma,Hak-Ling Ma,Bennett D. Grimm,Michael L. Hulsey,Harold M. McClure,Janet M. McNicholl,Bernard Moss,Harriet L. Robinson,Harriet L. Robinson +25 more
TL;DR: DNA priming followed by a recombinant modified vaccinia Ankara (rMVA) booster has controlled a highly pathogenic immunodeficiency virus challenge in a Rhesus macaque model, providing hope that a relatively simple multiprotein DNA/MVA vaccine can help to control the AIDS epidemic.
Journal ArticleDOI
Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations.
Harriet L. Robinson,David C. Montefiori,R P Johnson,Kelledy Manson,M. L. Kalish,J. D. Lifson,Tahir A. Rizvi,Shan Lu,Shiu Lok Hu,Gail P. Mazzara,Dennis Panicali,James G. Herndon,Rhona L. Glickman,M A Candido,S. L. Lydy,Michael S. Wyand,Harold M. McClure +16 more
TL;DR: The most promising containment of challenge infections was achieved by intradermal DNA priming followed by recombinant fowl pox virus booster immunizations, which did not require neutralizing antibody and was active for a series of challenges.
Journal ArticleDOI
Differential rearing affects corpus callosum size and cognitive function of rhesus monkeys.
TL;DR: Rearing environment was associated with sustained differences in cross-hemispheric projections, white matter volume and cognitive performance, and cognitive deficits exhibited by the NURSERY animals were significantly correlated with the alterations found in the CC.
Journal ArticleDOI
Patterns of cognitive decline in aged rhesus monkeys.
James G. Herndon,Mark B. Moss,Mark B. Moss,Douglas L. Rosene,Douglas L. Rosene,Ronald J. Killiany +5 more
TL;DR: Significant trends toward progressively higher impairment rates in advanced-aged and oldest-aged monkeys were observed for DNMS-acquisition, DRST-color and spatial reversal learning tasks, suggesting that a score based on only three tests may provide an adequate classification of global cognitive ability.