James N. Ingle

TL;DR: It is demonstrated here that ERα and ERβ regulate unique gene expression patterns in Hs578T cells, and such regulation likely is responsible for the observed isoform‐specific changes in cell proliferation.

TL;DR: Small, clinically unsuspected pericardial effusions appear to be relatively common in women with metastatic breast cancer and echocardiography performed on a routine basis, and nonsurgical therapy in patients with histologically proven or clinically suspected malignant pericARDial effusion was associated with a high incidence of progessive perICardial disease.

TL;DR: The data suggest that potent immunomodulators of bacterial origin, such as H. pylori NAP, can enhance the antitumor effect of oncolytic viruses and support the feasibility and potential of a combined viroimmunotherapy approach.

TL;DR: Evidence is provided that much of the controversy in the field with regard to the biological relevance of ERβ in breast cancer may be explained by variability in antibody sensitivity and specificity and the use of the MC10 antibody, in combination with highly specific antibodies targeting only full‐length ERβ, is likely to provide additional discriminatory features in breast cancers.

TL;DR: MetaBC is poorly responsive to NAC, with a pCR rate that is lower than expected in a predominantly TNBC cohort and in the absence of clinical trial enrollment, MetaBC patients with resectable disease should proceed directly to definitive operative management.