Setting of the learning problem consistency of learning processes bounds on the rate of convergence of learning processes controlling the generalization ability of learning processes constructing learning algorithms what is important in learning theory?.

The Nature of Statistical Learning Theory

We propose a generative model for text and other collections of discrete data that generalizes or improves on several previous models including naive Bayes/unigram, mixture of unigrams [6], and Hof-mann's aspect model, also known as probabilistic latent semantic indexing (pLSI) [3]. In the context of text modeling, our model posits that each document is generated as a mixture of topics, where the continuous-valued mixture proportions are distributed as a latent Dirichlet random variable. Inference and learning are carried out efficiently via variational algorithms. We present empirical results on applications of this model to problems in text modeling, collaborative filtering, and text classification.

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Latent Dirichlet Allocation

THE DESIGN AND ANALYSIS OF EXPERIMENTS. By Oscar Kempthorne. New York, John Wiley and Sons, Inc., 1952. 631 pp. $8.50. This book by a teacher of statistics (as well as a consultant for \"experimenters\") is a comprehensive study of the philosophical background for the statistical design of experiment. It is necessary to have some facility with algebraic notation and manipulation to be able to use the volume intelligently. The problems are presented from the theoretical point of view, without such practical examples as would be helpful for those not acquainted with mathematics. The mathematical justification for the techniques is given. As a somewhat advanced treatment of the design and analysis of experiments, this volume will be interesting and helpful for many who approach statistics theoretically as well as practically. With emphasis on the \"why,\" and with description given broadly, the author relates the subject matter to the general theory of statistics and to the general problem of experimental inference. MARGARET J. ROBERTSON

The Design and Analysis of Experiments

The application of maximum likelihood techniques to the estimation of evolutionary trees from nucleic acid sequence data is discussed. A computationally feasible method for finding such maximum likelihood estimates is developed, and a computer program is available. This method has advantages over the traditional parsimony algorithms, which can give misleading results if rates of evolution differ in different lineages. It also allows the testing of hypotheses about the constancy of evolutionary rates by likelihood ratio tests, and gives rough indication of the error of the estimate of the tree.

Evolutionary trees from DNA sequences: A maximum likelihood approach

An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models Multivariate techniques, including classification and ordination, are then introduced Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature The book is supported by a website that provides all data sets, questions for each chapter and links to software

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Experimental Design and Data Analysis for Biologists

Objective priors for sequential experiments are considered. Common priors, such as the Jeffreys prior and the reference prior, will typically depend on the stopping rule used for the sequential experiment. New expressions for reference priors are obtained in various contexts, and computational issues involving such priors are considered.

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Objective Bayesian analysis under sequential experimentation

We consider estimation of the parameters of a Gaussian Stochastic Process (GaSP), in the context of emulation (approximation) of computer models for which the outcomes are real-valued scalars. The main focus is on estimation of the GaSP parameters through various generalized maximum likelihood methods, mostly involving finding posterior modes; this is because full Bayesian analysis in computer model emulation is typically prohibitively expensive. The posterior modes that are studied arise from objective priors, such as the reference prior. These priors have been studied in the literature for the situation of an isotropic covariance function or under the assumption of separability in the design of inputs for model runs used in the GaSP construction. In this paper, we consider more general designs (e.g., a Latin Hypercube Design) with a class of commonly used anisotropic correlation functions, which can be written as a product of isotropic correlation functions, each having an unknown range parameter and a fixed roughness parameter. We discuss properties of the objective priors and marginal likelihoods for the parameters of the GaSP and establish the posterior propriety of the GaSP parameters, but our main focus is to demonstrate that certain parameterizations result in more robust estimation of the GaSP parameters than others, and that some parameterizations that are in common use should clearly be avoided. These results are applicable to many frequently used covariance functions, e.g., power exponential, Mat{e}rn, rational quadratic and spherical covariance. We also generalize the results to the GaSP model with a nugget parameter. Both theoretical and numerical evidence is presented concerning the performance of the studied procedures.

Robust Gaussian Stochastic Process Emulation

Optimal robust credible sets for contaminated priors

Let $X = (X_1, X_2, X_3)$ be a random vector with density $f(x - \theta)$, where $\theta = (\theta_1, \theta_2, \theta_3)$ is unknown. It is desired to estimate $(\theta_1, \theta_2)$ using an estimator $(\delta_1(X), \delta_2(X))$, and under a loss function $L(\delta_1 - \theta_1, \delta_2 - \theta_2)$. (Note that $\theta_3$ is a nuisance parameter.) Under certain conditions on $f$ and $L$, it is shown that the best invariant estimator of $(\theta_1, \theta_2)$ is inadmissible.

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Inadmissibility Results for the Best Invariant Estimator of Two Coordinates of a Location Vector

Informally, "Information Inconsistency" is the property that has been observed in many Bayesian hypothesis testing and model selection procedures whereby the Bayesian conclusion does not become definitive when the data seems to become definitive. An example is that, when performing a t-test using standard conjugate priors, the Bayes factor of the alternative hypothesis to the null hypothesis remains bounded as the t statistic grows to infinity. This paper shows that information inconsistency is ubiquitous in Bayesian hypothesis testing under conjugate priors. Yet the title does not fully describe the paper, since we also show that theoretically recommended priors, including scale mixtures of conjugate priors and adaptive priors, are information consistent. Hence the paper is simply a forceful warning that use of conjugate priors in testing and model selection is highly problematical, and should be replaced by the information consistent alternatives.

James O. Berger

Papers

Objective Bayesian analysis under sequential experimentation

Robust Gaussian Stochastic Process Emulation

Optimal robust credible sets for contaminated priors

Inadmissibility Results for the Best Invariant Estimator of Two Coordinates of a Location Vector

On the Ubiquity of Information Inconsistency for Conjugate Priors