J
Jamie E. Smyth
Researcher at Illawarra Health & Medical Research Institute
Publications - 2
Citations - 328
Jamie E. Smyth is an academic researcher from Illawarra Health & Medical Research Institute. The author has contributed to research in topics: Hibarimicinone. The author has an hindex of 1, co-authored 2 publications receiving 189 citations. Previous affiliations of Jamie E. Smyth include University of Wollongong.
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A twist of nature--the significance of atropisomers in biological systems.
TL;DR: The ability of natural receptors to possess differential binding between atropisomers is an important factor when considering active and inactive atrop isomeric drugs, and has required the development of new techniques for atropselective synthesis of desired targets.
Journal ArticleDOI
The Detosylation of Chiral 1,2-Bis(tosylamides).
Jayden J. Gaston,Andrew J. Tague,Jamie E. Smyth,Nicholas M. Butler,Anthony C. Willis,Nico J. R. van Eikema Hommes,Haibo Yu,Timothy Clark,Paul A. Keller +8 more
TL;DR: In this paper, the use of Mg/MeOH with sufficient steric additions allows the facile synthesis of 1,2-diamines in 78-98% yields.