J
Jamie N. Jones
Researcher at University of Texas at Austin
Publications - 27
Citations - 859
Jamie N. Jones is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Crystal structure & Isoniazid. The author has an hindex of 15, co-authored 27 publications receiving 811 citations. Previous affiliations of Jamie N. Jones include Milliken & Company & Imperial College London.
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Journal ArticleDOI
Crystal Structure of Mycobacterium tuberculosis Catalase-Peroxidase.
Thomas Bertrand,Nigel A.J. Eady,Jamie N. Jones,Jesmin,Judit M. Nagy,Brigitte Jamart-Grégoire,Emma Lloyd Raven,Katherine A. Brown +7 more
TL;DR: The availability of a crystal structure for the M. tuberculosis catalase-peroxidase permits structural and functional effects of mutations implicated in causing elevated levels of isoniazid resistance in clinical isolates to be interpreted with improved confidence.
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The molecular structure of tetra-tert-butyldiphosphine: an extremely distorted, sterically crowded molecule
Sarah L. Hinchley,Heather E. Robertson,Konstantin B. Borisenko,Andrew R. Turner,Blair F. Johnston,Blair F. Johnston,David W. H. Rankin,M. Ahmadian,Jamie N. Jones,Alan H. Cowley +9 more
TL;DR: In this article, the molecular structure of tetra-tert-butyldiphosphine has been determined in the gas phase by electron diffraction using the new DYNAMITE method and in the crystalline phase by X-ray diffraction.
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Synthesis and characterization of a coordinated oxoborane: Lewis acid stabilization of a boron-oxygen double bond
TL;DR: The first example of a stable oxoborane monomer (LB=O) stabilized by complexation to AlCl3 has been prepared by the reaction of LAlCl2 with BCl3 followed by treatment with H2O in CH2Cl2.
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Enzyme-catalyzed mechanism of isoniazid activation in class I and class III peroxidases.
Roberta Pierattelli,Lucia Banci,Nigel A.J. Eady,Jacques Bodiguel,Jamie N. Jones,Peter C. E. Moody,Emma Lloyd Raven,Brigitte Jamart-Grégoire,Katherine A. Brown +8 more
TL;DR: An enzyme-catalyzed mechanism for INH activation is proposed that brings together structural, functional, and spectroscopic data from a variety of sources and establishes a new conceptual framework for testing hypotheses regarding the enzyme- catalyzed turnover of this compound in a number of heme peroxidases.
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Stable carbenes. Synthesis and properties of benzimidazol-2-ylidenes
Nikolai I. Korotkikh,G. F. Raenko,T. M. Pekhtereva,O. P. Shvaika,Alan H. Cowley,Jamie N. Jones +5 more
TL;DR: In this article, a new stable crystalline carbene, 1,3-bis(1-adamantyl)benzimidazol-2-ylidene, was synthesized by decomposition of 1, 3-bis (1-Ad)2, 3d-dihydro-1H-Benzimide-1.2-methylacetonitrile on heating under reduced pressure.