J
Jan Ihmels
Researcher at Weizmann Institute of Science
Publications - 15
Citations - 5657
Jan Ihmels is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 13, co-authored 15 publications receiving 5454 citations. Previous affiliations of Jan Ihmels include University of California, San Francisco & Howard Hughes Medical Institute.
Papers
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Journal ArticleDOI
Comparative Gene Expression Analysis by a Differential Clustering Approach: Application to the Candida albicans Transcription Program
TL;DR: This study systematically compared the transcription program of the fungal pathogen Candida albicans with that of the model organism Saccharomyces cerevisiae and revealed differences related to the differential requirement for mitochondrial function in the two yeasts.
Journal ArticleDOI
Strategy of Transcription Regulation in the Budding Yeast
TL;DR: The results suggest that the capacity to anticipate and prepare for environmentally-mediated changes in cell growth presented a major selection force during yeast evolution.
Journal ArticleDOI
Challenges and prospects in the analysis of large-scale gene expression data
Jan Ihmels,Sven Bergmann +1 more
TL;DR: The central challenges in the analysis of large data sets, and how they might be overcome, are discussed and a summary of other important methods from the literature is provided.
Patent
"Recurrent signature" identifies transcriptional modules
TL;DR: In this paper, a method for analyzing and identifying functional linkages between biological processes which are regulated in a coordinate manner is presented, where the groups of genes are identified with their corresponding cis-regulatory elements.
Global transcription profiles of C. albicans and their comparison with other yeast species.
TL;DR: The Differential Clustering Algorithm is a flexible algorithm that systematically analyzes differences, as well as similarities, in gene expression patterns that were used to identify important aspects of the transcriptional networks that have been rewired through the evolution of S. cerevisiae and C. albicans.