Janaki Abeynayake

TL;DR: A multiplexed assay on a plasmonic-gold platform for measuring IgG and IgA antibodies and IgG avidity against both Zika virus (ZIKV) and dengue virus (DENV) infections could enable specific diagnosis of ZIKV infection over other flaviviral infections.

TL;DR: A multiplex, real-time, reverse transcriptase-PCR for the detection, quantitation, and serotyping of dengue viruses in a single reaction demonstrates superior analytical and clinical performance, as well as simpler workflow compared to the hemi-nested RT-PCRs.

TL;DR: The first set of virologically confirmed homotypic DENV reinfections are described, which challenge the current understanding of DENV immunity and have important implications for modeling DENV transmission.

TL;DR: A laboratory-developed rRT-PCR proved more clinically sensitive than the FDA-approved CDC assay for DENV serotypes 1 to 4 when measured against a composite reference standard, with sensitivities of 97.4% versus 87.1%, respectively.

TL;DR: The design of an internally controlled real-time reverse transcriptase PCR (rRT-PCR) that detects all four DENV serotypes but does not distinguish between them is reported, which is believed to serve to lengthen the period during which a confirmed molecular diagnosis of DENV infection can be provided.